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| ID | Type | Description | Link |
|---|---|---|---|
| 2014-A00875-42 | Other Identifier | ANSM |
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Chikungunya is a viral disease transmitted by mosquitoes whose clinical feature is the early joint damage. Approximately 8% of patients have chronic arthropathy resembling to the rheumatoid polyarthritis. The EchoCHIK study we propose is in the context of the epidemic in Martinique which began in January 2014. It should give a better understanding of arthritis and juxtaarticular of CHIK and look for signs that may allow ultrasound predict the evolution of chronic arthropathy of CHIK.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Patient suspected of being infected by chikungunya | Patient (>= 45 ans) suspect d'infection par le virus du chikungunya et présentant des symptomes depuis moins de 10 jours |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| SF36 (QQoL) | Other | use of quality of life questionnaire (SF 36) ( at enrollment visit, at 3 month, at 6 month and at12 month for the following visits) |
|
| Measure | Description | Time Frame |
|---|---|---|
| Presence of sonographic signs observed during the initial scan: periarticular infiltration, effusion, positive Doppler, erosions. | Progression to chronic form defined by the persistence or recurrence of muscle symptoms (myalgia) and joints (arthralgia, arthritis) more than two months after the onset of symptoms of acute phase. | enrollement visit |
| Measure | Description | Time Frame |
|---|---|---|
| Presence of clinical and sonographic signs observed at each visit: arthralgia, arthritis clinics, periarticular infiltration, effusion, positive Doppler erosions. | 1 month, 3 month, 6 month and 12 month after the first symptoms of infection by chikungunya virus |
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Inclusion Criteria:
Exclusion Criteria:
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Recruitment will be done among the patients from the Fort-de-France hospital and came for a suspected infection by the chikungunya virus
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| Name | Affiliation | Role |
|---|---|---|
| Lauren Brunier-Agot, MD | CHU de Martinique | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| CHU de Martinique | Fort-de-France | 97200 | Martinique |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 17448935 | Background | Pialoux G, Gauzere BA, Jaureguiberry S, Strobel M. Chikungunya, an epidemic arbovirosis. Lancet Infect Dis. 2007 May;7(5):319-27. doi: 10.1016/S1473-3099(07)70107-X. | |
| 494034 | Background | Fourie ED, Morrison JG. Rheumatoid arthritic syndrome after chikungunya fever. S Afr Med J. 1979 Jul 28;56(4):130-2. |
| Label | URL |
|---|---|
| A destructive arthropathy following Chikungunya virus arthritis--a possible association | View source |
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| 7373626 | Background | Kennedy AC, Fleming J, Solomon L. Chikungunya viral arthropathy: a clinical description. J Rheumatol. 1980 Mar-Apr;7(2):231-6. |
| 6298956 | Background | Brighton SW, Prozesky OW, de la Harpe AL. Chikungunya virus infection. A retrospective study of 107 cases. S Afr Med J. 1983 Feb 26;63(9):313-5. |
| 17505252 | Background | Simon F, Parola P, Grandadam M, Fourcade S, Oliver M, Brouqui P, Hance P, Kraemer P, Mohamed AA, de Lamballerie X, Charrel R, Tolou H. Chikungunya infection: an emerging rheumatism among travelers returned from Indian Ocean islands. Report of 47 cases. Medicine (Baltimore). 2007 May;86(3):123-137. doi: 10.1097/MD/0b013e31806010a5. |
| 17554689 | Background | Taubitz W, Cramer JP, Kapaun A, Pfeffer M, Drosten C, Dobler G, Burchard GD, Loscher T. Chikungunya fever in travelers: clinical presentation and course. Clin Infect Dis. 2007 Jul 1;45(1):e1-4. doi: 10.1086/518701. Epub 2007 May 23. |
| 19945329 | Background | Bouquillard E, Combe B. A report of 21 cases of rheumatoid arthritis following Chikungunya fever. A mean follow-up of two years. Joint Bone Spine. 2009 Dec;76(6):654-7. doi: 10.1016/j.jbspin.2009.08.005. |
| 20004145 | Background | Larrieu S, Pouderoux N, Pistone T, Filleul L, Receveur MC, Sissoko D, Ezzedine K, Malvy D. Factors associated with persistence of arthralgia among Chikungunya virus-infected travellers: report of 42 French cases. J Clin Virol. 2010 Jan;47(1):85-8. doi: 10.1016/j.jcv.2009.11.014. Epub 2009 Dec 8. |
| 22693935 | Background | Ribera A, Degasne I, Jaffar Bandjee MC, Gasque P. [Chronic rheumatic manifestations following chikungunya virus infection: clinical description and therapeutic considerations]. Med Trop (Mars). 2012 Mar;72 Spec No:83-5. French. |
| 20171708 | Background | Manimunda SP, Vijayachari P, Uppoor R, Sugunan AP, Singh SS, Rai SK, Sudeep AB, Muruganandam N, Chaitanya IK, Guruprasad DR. Clinical progression of chikungunya fever during acute and chronic arthritic stages and the changes in joint morphology as revealed by imaging. Trans R Soc Trop Med Hyg. 2010 Jun;104(6):392-9. doi: 10.1016/j.trstmh.2010.01.011. Epub 2010 Feb 19. |
| 23302155 | Background | Gerardin P, Fianu A, Michault A, Mussard C, Boussaid K, Rollot O, Grivard P, Kassab S, Bouquillard E, Borgherini G, Gauzere BA, Malvy D, Breart G, Favier F. Predictors of Chikungunya rheumatism: a prognostic survey ancillary to the TELECHIK cohort study. Arthritis Res Ther. 2013 Jan 9;15(1):R9. doi: 10.1186/ar4137. |
| Destructive arthritis in a patient with chikungunya virus infection with persistent specific IgM antibodies | View source |
| Post-Epidemic Chikungunya Disease on Reunion Island: Course of Rheumatic Manifestations and Associated Factors over a 15-Month Period | View source |