Evaluation of the Dose Received by the Prostate With in Vivo Dosimetry in Patients Treated With Daily IGRT Associated With IMRT Using Two Repositioning Techniques for Localized Prostate Cancer

This study evaluates the dose received by the prostate with in vivo dosimetry when delivering image guided radiation therapy (IGRT) associated with intensity modulated radiation therapy (IMRT) for patients with localized prostate cancer using two repositioning techniques: fiduciary markers or soft tissues.

10 participants will receive a cone beam computed tomography (CBCT) repositioning, while the other 10 will receive a kV imaging of fiducial marker repositioning. The principal objective is to evaluate and compare the dose received by the prostate using two repositioning techniques.

Inclusion Criteria:

• male > 18 years
• carcinoma of the prostate histologically confirmed
• OMS 0-1
• localized stage
• favorable, intermediate and unfavorable groups according to NCCN or D'Amico classification
• patients must have signed a written informed consent form
• patients must be affiliated to a Social Health Insurance.

Exclusion Criteria:

• metastasis
• indication for pelvic radiation
• anticoagulant therapy
• lateral or bilateral hip replacement
• patient receiving an adult protective services
• Patient unable to comply with the required medical follow-up for geographic, social or psychological reasons