A Pilot Study to Assess the Amnesic Properties of Propofol in Pediatric Patients

A Pilot Study to Assess the Amnesic Properties of Propofol in Pediatric Patients

The goal of this study is to extend findings of propofol's effects on memory, as measured in volunteer research studies, to a clinical setting.

Inclusion Criteria:

• The patient must be between 4 and 14 yrs of age and be undergoing a therapeutic or diagnostic procedure with or without sedation
• The patient must be able to comprehend and perform the task (naming pictures)
• The patient must have a minimum weight of 8 kg

Exclusion Criteria:

• Allergy to propofol (for those patients requiring sedation)
• Procedure of short duration (< 15 min)
• Pregnancy
• Recent use (within 5 half-lives) of centrally acting medications that could affect concentration (e.g. diphenhydramine)