Functional Magnetic Resonance Imaging (fMRI) Study of Nasal Strips in Nasal Congestion

A Magnetic Resonance Imaging Study of Nasal Strips in Subjects With Nasal Congestion

The aim of the study is to evaluate the effect of the nasal strip (relative to the placebo strip) on the nasal passages using anatomical MRI scans and to demonstrate the effect of the strip on breathing correlated cortical activity, using interoceptive fMRI task and analysis techniques derived from physiological data collected during scanning.

Inclusion Criteria:

• Participants with a self-rating of at least 3 to 8 for nasal congestion on the numerical rating scale
• Participants with a nasal congestion frequency score of 1, 2, 3 or 4.

Exclusion Criteria:

• Evidence of obstructive nasal polyps, nasal tract structural malformations, visible open sores, sunburn, irritation, eczema or chronic skin condition on the face or nose
• Use of any medications like nasal decongestant, alpha adrenergic drugs, glucocorticoids and any current treatment which in the opinion of the investigator will affect nasal congestion
• Known or suspected intolerance or hypersensitivity to the study materials.