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| Name | Class |
|---|---|
| National Institute for Health Research, United Kingdom | OTHER_GOV |
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The aim of this study is to develop and assess the feasibility of a physiotherapy intervention for people with functional motor symptoms (also known as psychogenic neurological symptoms and conversion disorder). Participants will be randomised to receive the intervention or a "treatment as usual" control.
Participants will be recruited from outpatient neurology clinics at Queen Square. Those who consent to take part will complete baseline outcome measures (Time 1) before being randomised to either a Treatment as Usual control group or the Intervention group.
Treatment as Usual group -
A referral to community therapy for such patients is usual practice in the UK, although the form in which the community therapy is provided tends to be inconsistent across the UK. In most cases it will entail between 1 and 8 outpatient or domiciliary physiotherapy appointments. Some communities will have access to Occupational Therapy, which may entail supported practice and advice to increase independence with functional tasks and the provision of equipment. The provision of community therapy to participants will be monitored through the CSRI.
Intervention Group -
For participants allocated to the intervention group, a 5 day admission on the Day Hospital at the National Hospital for Neurology and Neurosurgery is arranged. The physiotherapy intervention will take place in the physiotherapy department. Participants will be admitted individually (and not in groups). Outside of physiotherapy times participants are encouraged to rest in the day hospital and complete a workbook. A single independent physiotherapist will be trained to deliver the intervention.
The participant (+/- family member) will attend an initial meeting with the consultant neurologist and the treating physiotherapist. The neurologist will perform a brief neurological assessment and confirm the diagnosis.
Both groups will be followed up at 6 months after recruitment to the study (Time 3). An independent assessor will administer the outcome measures.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Intervention | Experimental | 5 Day physiotherapy programme at the National Hospital for Neurology and Neurosurgery, Queen Square, London UK. |
|
| Treatment as usual | Active Comparator | Participants are referred to their local neuro-physiotherapy service and if appropriate placed on a waiting list for inpatient rehabilitation. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| 5 Day Physiotherapy Programme | Other | The experimental group will complete a 5 day physiotherapy programme consisting of education, movement retraining and a self management plan. |
| Measure | Description | Time Frame |
|---|---|---|
| Clinical Global Impression Scale of Change | Self rated 5 point Likert scale of change | Approximately 4 weeks after randomisation (this will be immediately after treatment for the experimental arm) and 6 months |
| Measure | Description | Time Frame |
|---|---|---|
| Short Form 36 | Baseline and 6 months | |
| Hospital Anxiety and Depression Scale | Baseline, approximately 4 weeks after randomisation and 6 months | |
| EQ-5D-5L |
| Measure | Description | Time Frame |
|---|---|---|
| Client Services Receipt Inventory (CSRI) | This questionnaire collects retrospective information about the use of health and social care services, income, employment and benefits. It can be used to calculate service costs and total costs of care. | Baseline and 6 month follow up |
Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Glenn Nielsen | UCL | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| The National Hospital for Neurology and Neurosurgery | London | WC1N 3BG | United Kingdom |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 27694498 | Derived | Nielsen G, Buszewicz M, Stevenson F, Hunter R, Holt K, Dudziec M, Ricciardi L, Marsden J, Joyce E, Edwards MJ. Randomised feasibility study of physiotherapy for patients with functional motor symptoms. J Neurol Neurosurg Psychiatry. 2017 Jun;88(6):484-490. doi: 10.1136/jnnp-2016-314408. Epub 2016 Sep 30. |
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| ID | Term |
|---|---|
| D003291 | Conversion Disorder |
| ID | Term |
|---|---|
| D013001 | Somatoform Disorders |
| D001523 | Mental Disorders |
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| ID | Term |
|---|---|
| D026741 | Physical Therapy Modalities |
| ID | Term |
|---|---|
| D013812 | Therapeutics |
| D012046 | Rehabilitation |
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| Physiotherapy | Other | Treatment as usual physiotherapy. The participant will be referred to their closest NHS outpatient neuro-physiotherapy service. |
|
| Baseline, approximately 4 weeks after randomisation and 6 months |
| Brief Illness Perception Questionnaire | Baseline, approximately 4 weeks after randomisation and 6 months |
| Work and Social Adjustment Scale | Baseline, approximately 4 weeks after randomisation and 6 months |
| Disabilities of the Arm, Shoulder and Hand (DASH) | self reported questionnaire of upper limb function | Baseline, approximately 4 weeks after randomisation and 6 months |
| Functional Mobility Scale | Scale of assistance required when walking 5, 50 and 500 metres. | Baseline, approximately 4 weeks after randomisation and 6 months |
| Psychogenic Movement Disorders Rating Scale (PMDRS) | Blind video analysis of movement | Baseline, approximately 4 weeks after randomisation and 6 months |
| Berg Balance Scale | Baseline, approximately 4 weeks after randomisation and 6 months |
| 10 metre Walk Test | timed walk over 10 metres | Baseline, approximately 4 weeks after randomisation and 6 months |