Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Class |
|---|---|
| First Affiliated Hospital of Zhejiang University | OTHER |
| Zhongda Hospital | OTHER |
| The First Affiliated Hospital of Zhengzhou University | OTHER |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
The purpose of the study is to evaluate the clinical outcomes and cost-effectiveness of different vascular access(arteriovenous fistula, tunneled cuffed catheter and arteriovenous graft) in the elderly and very elderly with end-stage renal disease in China.
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| e-AVF group | Experimental | 120 elderly with end stage renal disease will undergo AVF creation. |
|
| e-TCC group | Experimental | 120 elderly with end stage renal disease will undergo TCC placement. |
|
| e-AVG group | Experimental | 60 elderly with end stage renal disease will undergo AVG creation. |
|
| ve-AVF group | Experimental | 80 very elderly with end stage renal disease will undergo AVF creation. |
|
| ve-TCC group | Experimental | 80 very elderly with end stage renal disease will undergo TCC placement. |
|
| ve-AVG group | Experimental | 40 very elderly with end stage renal disease will undergo AVG creation. |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| AVF creation | Procedure |
|
| |
| Measure | Description | Time Frame |
|---|---|---|
| The patency rate of vascular access | Including primary and secondary patency rate.Blood flow can be above 500 mL/min in a mature arteriovenous fistula by ultrasound scan and 4 times of body weight (Kg*4 mL/min) in a arteriovenous graft or tunneled cuffed catheter in dialysis practice. | 2 years |
| Effect of vascular access construction on ventricular volumes and left ventricular remodeling | Assessed by doppler echocardiography | 2 years |
| Effect of vascular access construction on brain MRI and cognitive functionslesions and cognitive function | Cognitive functions are assessed by psychic and autonomy scores | 2 years |
| Measure | Description | Time Frame |
|---|---|---|
| Complications of vascular access | Described as %.Complications including bleeding, infection, thrombosis, artery steal syndrome, heart failure, inadequate dialysis, etc. | 2 years |
| Cost-effectiveness of different vascular access |
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Xiaohong Hu, master | Contact | +8615026520819 | huxiaohong8305@163.com |
| Name | Affiliation | Role |
|---|---|---|
| Changlin Mei, master | Division of Nephrology, Shanghai ChangZheng Hospital | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Shanghai Changzheng Hospital | Shanghai | 200003 | China |
Not provided
| ID | Term |
|---|---|
| D007676 | Kidney Failure, Chronic |
| D001164 | Arteriovenous Fistula |
| ID | Term |
|---|---|
| D051436 | Renal Insufficiency, Chronic |
| D051437 | Renal Insufficiency |
| D007674 | Kidney Diseases |
| D014570 | Urologic Diseases |
Not provided
Not provided
| Sichuan Provincial People's Hospital |
| OTHER |
| The Second Affiliated Hospital of Dalian Medical University | OTHER |
| Beijing Haidian Hospital | OTHER |
Not provided
Not provided
Not provided
Not provided
Not provided
|
| TCC placement |
| Procedure |
|
|
| AVG creation | Procedure |
|
|
Described as $.The cost including medical expenses and non-medical expenses.
| 2 years |
| Hospitalization rate due to vascular access. | 2 years |
| Mortality due to vascular access | 2 years |
| D052776 |
| Female Urogenital Diseases |
| D005261 | Female Urogenital Diseases and Pregnancy Complications |
| D000091642 | Urogenital Diseases |
| D052801 | Male Urogenital Diseases |
| D002908 | Chronic Disease |
| D020969 | Disease Attributes |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D001165 | Arteriovenous Malformations |
| D054079 | Vascular Malformations |
| D018376 | Cardiovascular Abnormalities |
| D002318 | Cardiovascular Diseases |
| D016157 | Vascular Fistula |
| D014652 | Vascular Diseases |
| D000013 | Congenital Abnormalities |
| D009358 | Congenital, Hereditary, and Neonatal Diseases and Abnormalities |
| D005402 | Fistula |
| D020763 | Pathological Conditions, Anatomical |