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| ID | Type | Description | Link |
|---|---|---|---|
| 2013-A01097-38 | Registry Identifier | n°ID RCB |
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| Name | Class |
|---|---|
| Act For Chronic Diseases | OTHER |
| HP2 laboratory INSERM U1042 | UNKNOWN |
| University Grenoble Alps | OTHER |
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The main objective of the study is to identify the determinant of sleep characteristics of obese patients attempting a tertiary clinical center for obesity management, including bariatric surgery.
More accurately the questions addressed are:
Adult obese patients, attempting a tertiary medical center for the management of their obesity, are asked to participate in a cohort study. Data issued from routine clinical practice are collected.
Medical history and actual medical condition:
All patients who do not have a previously known sleep apnea syndrome are evaluated by nocturnal polygraphy.
Lifestyle and sleep habits, as well as social and economic characteristics, are assessed by questionnaires.
Patients are asked to provide blood sample to constituate a serum bank and gene bank.
Patients are asked, if undergoing bariatric surgery, to provide subcutaneous and visceral fat.
When patients benefit from bariatric surgery, follow-up data are collected at 3 months, 6 months, 12 months after bariatric surgery and yearly after that for at least 5 years.
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| Measure | Description | Time Frame |
|---|---|---|
| Sleep breathing disorders | Evolution of sleep breathing disorders during obesity management, especially after bariatric surgery | 5 years |
| Measure | Description | Time Frame |
|---|---|---|
| Sleep habits | Evolution of sleep habits during obesity care, especially after bariatric surgery | 5 years |
| Measure | Description | Time Frame |
|---|---|---|
| Metabolic diseases | Evolution of metabolic diseases during obesity care, especially after bariatric surgery | 5 years |
| Other respiratory diseases | Evolution of other respiratory diseases during obesity care, especially after bariatric surgery |
Inclusion Criteria:
Exclusion Criteria:
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Adult patients with class II or class III obesity (Body mass index ≥ 35kg/m²)
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Anne-Laure Borel, Pr MD PhD | Contact | +33 476 765 509 | alborel@chu-grenoble.fr | |
| Matthieu Lesgoirres | Contact | mlesgoirres@chu-grenoble.fr |
| Name | Affiliation | Role |
|---|---|---|
| Anne-Laure Borel, Pr MD PhD | University Hospital, Grenoble | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Grenoble University Hospital | Recruiting | Grenoble | Auvergne-Rhône-Alpes | 38043 | France |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 41092584 | Derived | Borel AL, Van Ngo TH, Coumes S, Pepin JL, Abba J, Tamisier R, Tonetti G, Suzeau P, Reche F, Bailly S. Cluster analysis in subjects living with obesity and association with bariatric surgery outcomes: The severe obesity outcome network cohort. Clin Nutr. 2025 Nov;54:210-219. doi: 10.1016/j.clnu.2025.09.022. Epub 2025 Oct 4. | |
| 33230959 |
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| ID | Term |
|---|---|
| D009765 | Obesity |
| D020181 | Sleep Apnea, Obstructive |
| ID | Term |
|---|---|
| D050177 | Overweight |
| D044343 | Overnutrition |
| D009748 | Nutrition Disorders |
| D009750 | Nutritional and Metabolic Diseases |
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Serum bank, gene bank, tissue bank (subcutaneous fat, visceral fat)
| 5 years |
| Complications of bariatric surgery | Recording of complications after bariatric surgery | 5 years |
| Guggino J, Coumes S, Wion N, Reche F, Arvieux C, Borel AL. Effectiveness and Safety of Bariatric Surgery in Patients with End-Stage Chronic Kidney Disease or Kidney Transplant. Obesity (Silver Spring). 2020 Dec;28(12):2290-2304. doi: 10.1002/oby.23001. |
| D001835 |
| Body Weight |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D012891 | Sleep Apnea Syndromes |
| D001049 | Apnea |
| D012120 | Respiration Disorders |
| D012140 | Respiratory Tract Diseases |
| D020919 | Sleep Disorders, Intrinsic |
| D020920 | Dyssomnias |
| D012893 | Sleep Wake Disorders |
| D009422 | Nervous System Diseases |