The purpose of this study is to characterize the frequency of TTR mutations in subjects suspected of having cardiac amyloidosis

Inclusion Criteria:

• Males or females >18 years old
• History of evidence suggestive of cardiac amyloidosis
• Subject is willing and able to comply with protocol required assessments and provide written informed consent

Exclusion Criteria:

• Known diagnosis of primary (AL) amyloidosis
• Known diagnosis of hereditary cardiomyopathy or cardiomyopathy due to aortic stenosis
• Patient is currently pregnant

Subjects Suspected of Having Familial Amyloidotic Cardiomyopathy (FAC)