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| Name | Class |
|---|---|
| University of Groningen | OTHER |
| Centre Hospitalier Régional de la Citadelle | OTHER |
| RWTH Aachen University | OTHER |
| University of Auckland, New Zealand |
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A primary aim of anaesthesia is to prevent awareness of surgery; ablation of the experience of surgery is the most secure way to prevent awareness with recall. Fortunately the incidence of awareness with recall (the patient can spontaneously remember the intraoperative event) is very rare (0.1-0.2%). However the investigators systematic review suggests that consciousness of intraoperative events may occur in approximately 37% of patients in experimental studies (as identified by the validated clinical procedure the isolated forearm test that does not require postoperative recall of the event). In this international cohort study, recruiting a minimum sample of 200 patients, the investigators will investigate the incidence of anaesthesia awareness (as identified by the isolated forearm test) following the induction of anaesthesia and before surgery.
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| Measure | Description | Time Frame |
|---|---|---|
| Incidence of isolated forearm test responsiveness following laryngoscopy and intubation | Following induction of anaesthesia, and securing the airway (laryngoscopy and intubation) the patient will be asked to squeeze the anaesthetist's hand as a surrogate of awareness under anaesthesia. | The test will occur within one minute of securing the airway (laryngoscopy and intubation). |
| Measure | Description | Time Frame |
|---|---|---|
| Incidence of isolated forearm test responsiveness before laryngoscopy and intubation | Following induction of anaesthesia, and prior to securing the airway (before laryngoscopy and intubation) if safe to do so, the patient will be asked to squeeze the anaesthetist's hand as a surrogate of anaesthesia awareness. | The test will occur in the minute prior to securing the airway (laryngoscopy and intubation). |
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Inclusion Criteria:
Exclusion Criteria:
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Adult patients undergoing anaesthesia requiring intubation and layngoscopy
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| Name | Affiliation | Role |
|---|---|---|
| Robert D Sanders, MBBS PhD FRCA | University of Wisconsin, Madison | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University of Michigan | Ann Arbor | Michigan | United States | |||
| University of Wisconsin |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 29121278 | Derived | Gaskell AL, Hight DF, Winders J, Tran G, Defresne A, Bonhomme V, Raz A, Sleigh JW, Sanders RD. Frontal alpha-delta EEG does not preclude volitional response during anaesthesia: prospective cohort study of the isolated forearm technique. Br J Anaesth. 2017 Oct 1;119(4):664-673. doi: 10.1093/bja/aex170. |
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| OTHER |
| University of Michigan | OTHER |
| University of Witten/Herdecke | OTHER |
| University College London Hospitals | OTHER |
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| Incidence of anaesthesia awareness with recall | After the operation and emergence from anaesthesia, and within 24 hours of the operation, the patient will be asked, using the structured Modified Brice questionnaire, about recall of intraoperative events (anaesthesia awareness). | Within 24 hours of the operation |
| Patient satisfaction questionnaire | Within 24 hours of the operation and emergence from anaesthesia, the patient will be asked to complete a patient satisfaction questionnaire rating the anaesthetic care they received. This will cover the preoperative information they were given, their emergence from anaesthesia, their pain control, experience of nausea and vomiting and their general experience. They will be asked to rate their care from four options: very satisfied, satisfied, dissatisfied and very dissatisfied. | Within 24 hours of the operation and emergence from anaesthesia |
| Madison |
| Wisconsin |
| United States |
| University of Auckland | Hamilton | Waikato Region | New Zealand |