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The purpose of this study is to determine the effectiveness of RXI-109 in reducing the recurrence of hypertrophic scar formation following elective revision of a pre-existing hypertrophic scar.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| RXI-109 | Experimental | RXI-109 dosed at the site of the revised hypertrophic scar |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| RXI-109 | Drug |
|
| Measure | Description | Time Frame |
|---|---|---|
| Reducing the recurrence of hypertrophic scar after scar revision surgery | To evaluate the effectiveness of RXI-109 in reducing the recurrence of hypertrophic scar formation following elective scar revision surgery by review of photographic results and Patient and Observer Scar Assessment Scales. | 9 months |
| Measure | Description | Time Frame |
|---|---|---|
| Safety evaluation of RXI-109 | To assess severity and frequency of reported adverse events and clinically-relevant changes in laboratory testing after elective revision of a hypertrophic scar | 9 months |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Pamela Pavco, PhD | RXi Pharmaceuticals | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Beverly Hills | California | 90210 | United States | |||
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| ID | Term |
|---|---|
| D017439 | Cicatrix, Hypertrophic |
| D002921 | Cicatrix |
| ID | Term |
|---|---|
| D005355 | Fibrosis |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
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| Lake Worth |
| Florida |
| 33461 |
| United States |
| Chicago | Illinois | 60611 | United States |
| St Louis | Missouri | 63141 | United States |
| Huntersville | North Carolina | 28028 | United States |
| San Pedro Sula | 21104 | Honduras |