A Study to Evaluate the Effectiveness and Safety of RXI 109 on the Outcome of Revised Hypertrophic Scars

An Open-Label, Multi-Center, Prospective, Within-Subject Controlled, Phase 2a Study to Evaluate the Effectiveness and Safety of RXI 109 on the Outcome of Scar Revision Surgery for Hypertrophic Scars in Healthy Adults

The purpose of this study is to determine the effectiveness of RXI-109 in reducing the recurrence of hypertrophic scar formation following elective revision of a pre-existing hypertrophic scar.

Inclusion Criteria:

• Adults, 21-55 years of age
• General good health
• Previous surgery or injury resulting in a hypertrophic scar

Exclusion Criteria:

• Scars on the face or front of neck may not be included in the trial
• Use of tobacco or nicotine-containing products
• Pregnant or lactating