EXPLORE: A Natural History Study of Acute Hepatic Porphyria (AHP)

A Natural History Study of Acute Hepatic Porphyria (AHP) Patients With Recurrent Attacks

The purpose of this study is to characterize the natural history and clinical management of Acute Hepatic Porphyria (AHP) patients with recurring attacks.

Inclusion Criteria:

• Males and females aged >/= 12 years
• Diagnosis of AHP [acute intermittent porphyria (AIP), variegate porphyria (VP), hereditary coproporphyria (HCP) and aminolevulinic acid dehydratase (ALAD) deficient porphyria (ADP)]
• Porphyria attacks in the past 12 months or receiving treatment to prevent attacks
• Willing to provide written informed consent, medical records, and to comply with study requirements

Exclusion Criteria:

• Current participation in a clinical trial of an investigational product