To assess the effectiveness of the synthetic analogue of prostacyclin in postembolic residual pulmonary hypertension.

Inclusion Criteria:

• Patients with pulmonary embolism after undergone surgical treatment (intravascular thrombolysis, catheter thrombus fragmentation)
• Patients with preserved thromboembolism in the pulmonary circulation system and mean pressure in the pulmonary artery of more than 25 mm Hg

Exclusion Criteria:

• Patient did not sign the informed consent.
• Mean pulmonary artery pressure after surgical treatment less than 25 mm Hg
• Age above 75 years.
• Patients with an increased risk of bleeding - including gastric ulcer and 12 duodenal ulcer in acute, hemorrhagic stroke.
• Severe coronary artery disease (unstable angina, myocardial infarction within the last 6 months).
• Acute heart failure or CHF IV in NYHA.
• Severe arrhythmias.
• Pregnancy, lactation.
• The presence of severe diseases of other organ systems that may result in death during the first year after surgery.