This trial is conducted in the United States of America (USA). The aim of the trial is to investigate safety, tolerability and pharmacokinetics (the exposure of the trial drug in the body) for single doses of NNC9204-0530 alone and in combination with liraglutide in overweight to obese but otherwise healthy male subjects.

Inclusion Criteria:

• Male, age between (both inclusive) 18 and 55 years at the time of signing inform consent
• Overweight or obese but otherwise healthy male subjects; BMI of between or equal to 27.0 and 35.0 kg/m^2

Exclusion Criteria:

• Thyroid stimulating hormone values outside 0.4-6.0 mIU/l
• HbA1c (glycated hemoglobin) above or equal to 6.5%
• Any clinically relevant ECG (electrocardiogram) findings (e.g. 2nd or 3rd degree AV-block), in particular subjects with repeated demonstration of a QTcF (QT interval corrected by Fridericia formula) interval above 430 ms
• A history of additional risk factors for Torsades de pointes (e.g., heart failure, hypokalemia, family history of Long QT Syndrome)
• The use of concomitant medications that prolong the QT/QTc interval
• Obesity caused by endocrinology disorders (e.g. Cushing's Syndrome)
• Personal or family history of medullary thyroid carcinoma or multiple endocrine neoplasia syndrome type 2
• Calcitonin above 50 ng/L
• History of pancreatitis (acute or chronic)