• Evaluation of safety and effectiveness of implantable LAA occluder in clinical practice
• Indication: For which reasons is the indication for implantation of LAA-Occluder put for patients with atrial fibrillation?
• Safety: How save is the implantation of LAA-Occluders?
• Effectiveness: How effective is implantation of LAA-Occluders in daily clinical practice?
• Concomitant treatment: Which concomitant treatment is prescribed for patients with LAA-Occluder?

LAARGE aims to show the care reality of patients whose left atrial appendage (LAA) is closed by an implantable medical device. In particular the following questions should be answered:

• Indication: For which reasons is the indication for implantation of LAA-Occluder put for patients with atrial fibrillation?
• Safety: How save is the implantation of LAA-Occluders (procedural, in hospital and in the long term course)? How frequent are bleeding complications and what is the relation of observed and expected bleeding complications (according HAS-BLED score)?
• Effectiveness: How effective is implantation of LAA-Occluders in daily clinical practice (in hospital and in the long term course)? How frequent are strokes and what is the relation of observed and expected strokes (according CHADS-VASC score)?
• Concomitant treatment: Which concomitant treatment is prescribed for patients with LAA-Occluder?

Inclusion Criteria:

Intention to laa occluder

Exclusion Criteria:

Missing informed consent

all patients with an performed or planned LAA -Occluder