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Introduction: the global sugar consumption has increased in the past 50 years and their abusive intake is responsible for the insulin resistance and causes the metabolic syndrome - obesity, diabetes mellitus, hypertension and coronary heart disease. Objective: To evaluate the effect of scheduled diet without glucose as treatment of labyrinthine disorders associated with glucose-insulin index. Study Design: A prospective randomized controlled trial. Patients and Methods: A study conducted at the University of São Paulo with 51 patients divided into two groups: Diet Group (DG) that comprises subjects treated with fractionated diet with glucose restriction and control group (CG) where individuals were not counseled regarding diet. Patients underwent computerized dynamic posturography - sensory organization test (CDP - SOT) and Visual Analog Scale (VAS) in the first and thirtieth days of the study.
51 patientes with dizziness and glucose intolerance diagnosed by the glucose tolerance test were selected.
The subjects were submited to CDP SOT conditions and a visual analogue scale to measure his self perception about dizziness.
Then, they were randomized in two groups: with and without fractioned diet without glucose during 30 days.
The CDP was repeated in order to verify a statistical difference of SOT condition 5 that reflects the individual hability to maintain the own posture with the vestibule solely and CS - that represents the final balance situation.
The VAS was repeated too in order to verify the self perception of the dizziness after diet.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| control | Placebo Comparator | Usual diet without any orientation |
|
| fractioned diet without glucose | Active Comparator | Fractioned diet without glucose |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| fractioned diet without glucose | Behavioral | Patients were divided into two groups: Diet Group was treated with placebo pills and glucose restrictive and fractionated diet. Control Group received only placebo pills. All individuals had their vestibular function evaluated by Computerized Dynamic Posturography and done visual analogue scale (VAS) in the first day and 30 days after diet intervention |
| Measure | Description | Time Frame |
|---|---|---|
| Assessment of equilibrium score through the computerized dynamic posturography (CDP) in 51 patients | 30 days |
| Measure | Description | Time Frame |
|---|---|---|
| Self perception of dizziness mesured by the visual analogue scale | 30 days |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Roseli SM Bittar, MD, PhD | University of Sao Paulo | Principal Investigator |
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| ID | Term |
|---|---|
| D018149 | Glucose Intolerance |
| D014717 | Vertigo |
| ID | Term |
|---|---|
| D006943 | Hyperglycemia |
| D044882 | Glucose Metabolism Disorders |
| D008659 | Metabolic Diseases |
| D009750 | Nutritional and Metabolic Diseases |
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| ID | Term |
|---|---|
| D005947 | Glucose |
| ID | Term |
|---|---|
| D006601 | Hexoses |
| D009005 | Monosaccharides |
| D000073893 | Sugars |
| D002241 | Carbohydrates |
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|
| D015837 | Vestibular Diseases |
| D007759 | Labyrinth Diseases |
| D004427 | Ear Diseases |
| D010038 | Otorhinolaryngologic Diseases |
| D009461 | Neurologic Manifestations |
| D009422 | Nervous System Diseases |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |