The hypothesis was to establish whether the use of PrevinC administered nasally 2-3 times a day will prevent upper respiratory infections in otherwise healthy adults working in child day care centers.

Inclusion Criteria:

• Subject must provide written informed consent prior to the conduct of any study
• Male or female
• 18-65 years of age
• Inclusive
• Employed by one of seven selected Day Care Centers

Exclusion Criteria:

• Recent symptoms of upper respiratory infection, respiratory disease
• Received medication for colds or allergies within 3 weeks of enrolling
• Had nasal surgery within 2 months of enrolling
• Had a pierced nose or wore nose jewelry