Prevalence of BRCA in Patients With Ovarian Cancer

Prevalence of BRCA in Patients With Primary or Platinum Sensitive Recurrent Ovarian Cancer.

The aim of this prospective registration and translational research study is to evaluate the praevalence of BRCA regarding germline and somatic mutations.

Explorative analysis will be performed.

Inclusion Criteria:

• Female ovarian cancer patients aged >= 18 years.
• Women with first diagnosis of epithelial ovarian cancer OR women diagnosed with platinum-sensitive recurrent ovarian cancer.
• Multiple platinum based prior therapies are allowed.

Exclusion Criteria:

• Non-epithelial ovarian malignancy.
• Platinum-resistant or refractory disease.
• Paraffin embedded tumor samples not available.