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The investigators wish to study the effect of Vitamin D on the development of autism in children. The investigators will also investigate the environmental and genetic influences on the level of Vitamin D in children with autism.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Autistic Children | Children diagnosed with autism spectrum disorder according to the criteria of the Diagnostic Statistical Manual-V will have blood samples taken for laboratory analysis. |
| |
| Healthy Children | Children with no developmental or physical diseases will have blood samples taken for laboratory analysis. |
| |
| Children with Attention Deficit Disorder | Blood samples from children with Attention Deficit Disorder will be measured for Vitamin D and oxidative stress markers. |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Blood Samples | Other |
|
| Measure | Description | Time Frame |
|---|---|---|
| Level of Vitamin D | Blood samples of patients with and without autism with be taken and the level of vitamin D in their serum will be determined (international units). | One day |
| Measure | Description | Time Frame |
|---|---|---|
| Effect of environment on Vitamin D level | All participant blood samples will be measured for levels of oxidative stress markers and antioxidants. | One week |
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Inclusion Criteria:
Exclusion Criteria:
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Children with autism who have presented to the Child Development Institute at the Hillel Yaffe Medical Center and from pediatric neurology community clinics. The control groups include healthy age-matched children and children with Attention Deficit Disorder (ADD) who have presented to the Child Development Institute at the Hillel Yaffe Medical Center and from pediatric neurology community clinics.
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Muhammad Mahajnah, MD, PhD | Contact | 972-5-624-6959 | mohamedm@hy.health.gov.il |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Hillel Yaffe Medical Center | Hadera | 38100 | Israel |
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| ID | Term |
|---|---|
| D001321 | Autistic Disorder |
| ID | Term |
|---|---|
| D000067877 | Autism Spectrum Disorder |
| D002659 | Child Development Disorders, Pervasive |
| D065886 | Neurodevelopmental Disorders |
| D001523 | Mental Disorders |
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| ID | Term |
|---|---|
| D001800 | Blood Specimen Collection |
| ID | Term |
|---|---|
| D013048 | Specimen Handling |
| D019411 | Clinical Laboratory Techniques |
| D019937 | Diagnostic Techniques and Procedures |
| D003933 | Diagnosis |
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| D011677 | Punctures |
| D013514 | Surgical Procedures, Operative |
| D008919 | Investigative Techniques |