Topical Instillation of Tranexamic Aacid in Bronchoscopy to Decrease Bleeding During Entobronchial & Transbronchial Biopsiy: a Prospective Double Blind Placebo Controlled Study

Bleeding during transbronchial ro endobronchial biopsy is rather a common complication.

Mostly this is an insignificant bleeding, but in 3% of the biopsies there is a substantial amount of bleeding that requires a special treatment or follow up.

The goal of this study is to examine whether submission of tranexamic acid during the biopsy could diminish the amount of bleeding.

Inclusion Criteria:

• Patient that are candidates to endobronchial or transcronchial biopsy

Exclusion Criteria:

• S/P MI or CVA or PE or DVT .
• S/P thrombophilia.
• Patients under coagulation therpay
• Chronic Renal Failure
• Pregnancy