Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Bleeding during transbronchial ro endobronchial biopsy is rather a common complication.
Mostly this is an insignificant bleeding, but in 3% of the biopsies there is a substantial amount of bleeding that requires a special treatment or follow up.
The goal of this study is to examine whether submission of tranexamic acid during the biopsy could diminish the amount of bleeding.
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| tranexamic acid | Experimental | tranexamic acid will be administrated using the bronchoscope |
|
| saline | Placebo Comparator | the saline will be administrated using an infusion during the biopsy. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| tranexamic acid | Drug |
| ||
| saline |
| Measure | Description | Time Frame |
|---|---|---|
| amount of bleeding | amount of bleedibg that will be calculated on the basis of the difference between the amount of saline that will be injected at the bronchoscopy and the blood and fluid that will be collected in the suction tank. | participants will be followed for the duration of hospital stay, an expected average of one day |
| Measure | Description | Time Frame |
|---|---|---|
| amount of erythrocytes | amount of erythrocytes by multiplying the Hematocrit and blood volume | participants will be followed for the duration of hospital stay, an expected average of one day |
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Not provided
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Liran Levy, MD | Contact | 6475189676 | dlev330@hadassah.org.il | |
| Liran Levy, MD | Contact | 6475189676 | levyliran361@gmail.com |
| Name | Affiliation | Role |
|---|---|---|
| Neville Berkman, MD | Hadassah Medical Organization | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Hadassah Medical Organization | Recruiting | Jerusalem | 91120 | Israel |
Not provided
Not provided
Not provided
Not provided
Not provided
|
| ID | Term |
|---|---|
| D014148 | Tranexamic Acid |
| D012965 | Sodium Chloride |
| ID | Term |
|---|---|
| D003509 | Cyclohexanecarboxylic Acids |
| D000146 | Acids, Carbocyclic |
| D002264 | Carboxylic Acids |
| D009930 | Organic Chemicals |
| D002712 | Chlorides |
| D006851 | Hydrochloric Acid |
| D017606 | Chlorine Compounds |
| D007287 | Inorganic Chemicals |
| D017670 | Sodium Compounds |
Not provided
Not provided