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The objective in this observational cohort study of young adults sampled at three intervals during the academic year is to ascertain if there is carriage of B. pertussis in asymptomatic individuals. We hypothesize that in asymptomatic college students there is no carriage of B. pertussis detectable by polymerase chain reaction (PCR) assay.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| No treatment | Young adults tested by PCR for B. pertussis carriage |
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| Measure | Description | Time Frame |
|---|---|---|
| Number of participants with B. pertussis by PCR in nasopharyngeal sample at first timepoint | Participants will be tested for B. pertussis by PCR at one visit in October 2014, 30 minutes. | 30 minutes |
| Measure | Description | Time Frame |
|---|---|---|
| Number of participants with B. pertussis by PCR in nasopharyngeal sample at second timepoint | Participants will be tested for B. pertussis by PCR at one visit in January 2015, 30 minutes. | 30 minutes |
| Measure | Description | Time Frame |
|---|---|---|
| Number of participants with B. pertussis by PCR in nasopharyngeal sample at third timepoint | Participants will be tested for B. pertussis by PCR at one visit in April 2015, 30 minutes. | 30 minutes |
Inclusion Criteria:
Exclusion Criteria:
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College-aged students/young adults
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University of Virginia Health System | Charlottesville | Virginia | 22908 | United States |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 21046700 | Background | Nuolivirta K, Koponen P, He Q, Halkosalo A, Korppi M, Vesikari T, Helminen M. Bordetella pertussis infection is common in nonvaccinated infants admitted for bronchiolitis. Pediatr Infect Dis J. 2010 Nov;29(11):1013-5. | |
| 24520981 | Background | Zhang Q, Yin Z, Li Y, Luo H, Shao Z, Gao Y, Xu L, Kan B, Lu S, Zhang Y, Li M, Liu M, Yao P, Zhao Z, He Q. Prevalence of asymptomatic Bordetella pertussis and Bordetella parapertussis infections among school children in China as determined by pooled real-time PCR: a cross-sectional study. Scand J Infect Dis. 2014 Apr;46(4):280-7. doi: 10.3109/00365548.2013.878034. Epub 2014 Feb 13. |
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