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The aim of this study, comparison of effects of sugammadex versus neostigmine/atropine combination on hemodynamic parameters and intraocular pressure during tracheal extubation.
This prospective, randomised study was designed to compare two reversal methods with respect to changes in IOP, heart rate and blood pressure during tracheal extubation period.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| sugammadex | Active Comparator |
| |
| neostigmine + atropine | Active Comparator |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| sugammadex | Drug | sugammadex 2 mg/kg |
| |
| neostigmine+atropine |
| Measure | Description | Time Frame |
|---|---|---|
| intraocular pressure | baseline, before applying reversal agent, after applying reversal agent, one, three, five and ten minutes after tracheal extubation |
| Measure | Description | Time Frame |
|---|---|---|
| heart rate | baseline, before applying reversal agent, after applying reversal agent, one, three, five and ten minutes after tracheal extubation | |
| blood pressure | baseline, before applying reversal agent, after applying reversal agent, one, three, five and ten minutes after tracheal extubation |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Anesthesiology and Reanimation Dept. Ordu University Training and Research Hospital | Altinordu | Ordu | 52100 | Turkey (Türkiye) |
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| Drug |
neostigmine 0,05 mg/kg + atropine 0,025 mg/kg |
|
| ID | Term |
|---|---|
| D000077122 | Sugammadex |
| ID | Term |
|---|---|
| D047408 | gamma-Cyclodextrins |
| D003505 | Cyclodextrins |
| D047028 | Macrocyclic Compounds |
| D011083 | Polycyclic Compounds |
| D003912 | Dextrins |
| D013213 | Starch |
| D005936 | Glucans |
| D011134 | Polysaccharides |
| D002241 | Carbohydrates |
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