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The aim is to study the effect of local anaesthesia (EMLA®) on pain associated with sterile water injections.
Sterile Water Injection (SWI) was previously shown to give good pain relief for lower-back pain during childbirth, chronic neck pain and ureterolithiasis. However, the pain associated with the injections remains problematic, and therefore it is important to find a less painful injection technique.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| EMLA patches and SWI | Experimental | EMLA patches 1.5 hrs before sterile water injections |
|
| EMLA patches and isotonic saline | Active Comparator | EMLA patches 1.5 hrs before isotonic saline |
|
| Placebo patches and SWI | Placebo Comparator | PLACEBO patches 1.5 hrs before sterile water injections |
|
| Placebo patches and isotonic saline | Placebo Comparator | PLACEBO patches 1.5 hrs before isotonic saline |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| EMLA patches | Other | EMLA patches 1.5 hrs before sterile water injections |
|
| Measure | Description | Time Frame |
|---|---|---|
| Self reported experience of injection pain measured by Visual Analogue Scale following Sterile Water Injections | Self reported experiences of pain with Visual Analogue Scale 0=no pain 10=worst imaginable pain | 15 minutes |
| Measure | Description | Time Frame |
|---|---|---|
| Self reported (questionnaire descriptive via email), self-reported experiences of side effects following Sterile Water injections | Self reported (questionnaire descriptive via email), self-reported experiences of of side effects following Sterile Water injections | 24 hours |
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Inclusion Criteria
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Lena B Mårtensson, Professor | University of Skövde | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| School of Health Sciences, University of Skövde | Skövde | SE-541 28 | Sweden |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 35105307 | Derived | Martensson LB, Gunnarsson BM, Karlsson S, Lee N, Bergh I. Effect of topical local anaesthesia on injection pain associated with administration of sterile water injections - a randomized controlled trial. BMC Anesthesiol. 2022 Feb 1;22(1):35. doi: 10.1186/s12871-022-01573-0. |
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| ID | Term |
|---|---|
| D010146 | Pain |
| ID | Term |
|---|---|
| D009461 | Neurologic Manifestations |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
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