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| ID | Type | Description | Link |
|---|---|---|---|
| P01DK043881 | U.S. NIH Grant/Contract | View source |
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| Name | Class |
|---|---|
| University of Washington | OTHER |
| VA Puget Sound Health Care System | FED |
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Patients with a ureteral or kidney stone that causes symptoms, like pain, frequently have small kidney stones that don't cause symptoms. If these small kidney stones are determined to be asymptomatic (not causing any problems or pain), then most urologists will simply remove the symptomatic ureteral stone and leave the additional stones in the kidneys. However, symptomatic kidney stones started as small stones that didn't cause symptoms. This means that the small stones remaining in the patient's kidney may cause problems later. The purpose of our research is to test if removing small stones from the kidney prevents future stone episodes.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Symptomatic stone removal | Other | Group 1 will receive the standard treatment of having only the symptomatic stone removed |
|
| Asymptomatic kidney stones and symptomatic stone removed | Other | Group 2 will include the step of having the asymptomatic kidney stones removed in addition to the symptomatic stone |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Symptomatic stone removal | Procedure | Symptomatic stone removal by the surgical procedures called Ureteroscopy or Percutaneous Nephrolithotomy |
|
| Measure | Description | Time Frame |
|---|---|---|
| Relapse of stone disease on the study side |
| annually up to 5 years after stone removal surgery |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| James E Lingeman, MD | Indiana University Health | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Indiana University Health | Indianapolis | Indiana | 46202 | United States | ||
| University of Minnesota |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 35947709 | Derived | Sorensen MD, Harper JD, Borofsky MS, Hameed TA, Smoot KJ, Burke BH, Levchak BJ, Williams JC Jr, Bailey MR, Liu Z, Lingeman JE. Removal of Small, Asymptomatic Kidney Stones and Incidence of Relapse. N Engl J Med. 2022 Aug 11;387(6):506-513. doi: 10.1056/NEJMoa2204253. |
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| Asymptomatic kidney stones and ureteral stone removed | Procedure | Asymptomatic kidney stones and symptomatic stone removal by the surgical procedure called Ureteroscopy |
|
| Minneapolis |
| Minnesota |
| 55455 |
| United States |
| University of Washington Medical Center Department of Urology | Seattle | Washington | 98195 9472 | United States |
| Veterans Administration Puget Sound Heath Care System | Seattle | Washington | 98195 | United States |
| ID | Term |
|---|---|
| D007669 | Kidney Calculi |
| ID | Term |
|---|---|
| D053040 | Nephrolithiasis |
| D007674 | Kidney Diseases |
| D014570 | Urologic Diseases |
| D052776 | Female Urogenital Diseases |
| D005261 | Female Urogenital Diseases and Pregnancy Complications |
| D000091642 | Urogenital Diseases |
| D052878 | Urolithiasis |
| D014545 | Urinary Calculi |
| D052801 | Male Urogenital Diseases |
| D002137 | Calculi |
| D020763 | Pathological Conditions, Anatomical |
| D013568 | Pathological Conditions, Signs and Symptoms |
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