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The investigators want to carry out a prospective study of 400 infertile Caucasian and Indian women who will undergo a controlled ovarian stimulation for in vitro fertilization (IVF). The investigators will collect data about ovarian reserve markers and also the results after ovarian stimulation in both ethnic groups.The aim is to identify differences in ovarian response after IVF stimulation between both groups.
A total of 200 Caucasian patients and 200 Indian patients who will attend the first or second IVF cycle will be included.
The date we will collect in both groups include the age, the body mass index, and the ovarian reserve markers like the antral follicle count (AFC), the follicle stimulation hormone (FSH) and antimullerian hormone (AMH) serum levels.
The investigators will also determine the number of oocytes retrieved and the metaphase two oocytes in both groups after IVF stimulation.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Caucasian women | 200 Caucasian infertile women undergoing their first or second IVF cycle | ||
| Indian women | 200 Indian women undergoing their first or second IVF cycle. |
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| Measure | Description | Time Frame |
|---|---|---|
| AMH levels produced by granulosa cells | AMH levels (ng/mL) as well as AFC in both ethnic groups. | day 1 |
| Measure | Description | Time Frame |
|---|---|---|
| Number of oocytes | The number of oocytes retrieved as well as the mature oocytes after IVF ovarian stimulation | day 1 |
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Inclusion Criteria:
Exclusion Criteria:
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Caucasian infertile women and Indican infertile women age < 42 years old, with both ovaries present, undergoing an IVF treatment due to male factor, tubal disease or previous failed IUI.
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| Name | Affiliation | Role |
|---|---|---|
| Carlos Iglesias, M.D. | IVI Madrid | Principal Investigator |
| Manish Banker, M.D. | NOVA IVI | Principal Investigator |
| Nalini Mahajan, M.D. | NOVA IVI | Principal Investigator |
| Leyre Herrero, Ph. D. | IVI Madrid | Principal Investigator |
| Antonio Pellicer, M.D. | IVI VALENCIA | Principal Investigator |
| Juan Antonio Garcia-Velasco, M.D. | IVI Madrid | Principal Investigator |
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