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| Name | Class |
|---|---|
| National Institute for Health Research, United Kingdom | OTHER_GOV |
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Attention Deficit/Hyperactivity Disorder (ADHD)is one of the most common mental health disorders of childhood. Children with ADHD often have poor attention, are restless and hyperactive and show impulsive behaviour.
It is important to detect ADHD so young people can have access to appropriate clinical interventions.
One of the most common ways ADHD is assessed is through the clinician's opinion; however, this can vary between clinicians and is thought to be one reason why ADHD may be mis-diagnosed. Using a more objective computer tasks may help improve our understanding of ADHD. One computer task is the QbTest.
The test presents different symbols to the child, and the child has to respond by pressing a button only when a target symbol appears. The test measures the child's attention, impulsivity and movement whilst doing this task.
Although the test is thought to be a valid measure, more research needs to be conducted on this measure to see whether it helps clinicians decision making.
To see whether this test helps clinicians make a diagnosis of ADHD and helps with medication decisions, children and young people will be asked to complete the task as part of their initial assessment for ADHD. Half the participants and their clinician will have access to the QbTest result; the other half will not have access to the QbTest result until the end of the study.
Participant's parents, teachers and the clinician will also be asked to complete some questionnaires about the child's symptoms and behaviour. If the child is diagnosed with ADHD and is given medication they will be asked to complete the task again on medication. The same set of questionnaires will be completed by the parents/teachers/clinicians.
The entire sample will be followed up at 6 months and asked to complete the questionnaires.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| QB Open | Active Comparator | Participants and their clinician will receive results of the Qb Test |
|
| Qb Blind | Other | Participants and their clinician will be blind to the results of the Qb test |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Qb Test | Other | Given to all participants but the results will be open or blind depending on arm allocation |
|
| Measure | Description | Time Frame |
|---|---|---|
| Number of clinic appointments until correct diagnosis confirmed | Number of clinic appointments until correct ADHD diagnosis is confirmed or excluded for the QBOpen (delivery of immediate QbTest feedback report) and QbBlind (delayed feedback of QbTest report) groups. | By 6 months |
| Measure | Description | Time Frame |
|---|---|---|
| Time to confirmation or exclusion of ADHD diagnosis (in days) and duration of clinic visits (in minutes). | Time to confirmation or exclusion of ADHD diagnosis (in days) and duration of clinic visits (in minutes). This will provide supporting evidence that a reduced number of clinic visits is associated with shorter overall time to diagnosis and reduced clinic time required for assessment. | Up to 6 months |
| Measure | Description | Time Frame |
|---|---|---|
| Degree of Confidence of diagnosis | Differences in degree of confidence of diagnosis between cases in QbOpen (QbO) and QbBlind (QbB) group. These variables will assess the utility of QbTest in aiding diagnosis (diagnostic certainty). | Up to 6 months |
| Stability in diagnosis and confidence between the QbO and QbB group |
Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Chris Hollis, MRC Psych, PhD | University of Nottingham, Nottingham HC Trust | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Central Manchester University Hospitals NHS Foundation Trust | Manchester | Greater Manchester | M13 9WL | United Kingdom | ||
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 25448628 | Background | Hall CL, Walker GM, Valentine AZ, Guo B, Kaylor-Hughes C, James M, Daley D, Sayal K, Hollis C. Protocol investigating the clinical utility of an objective measure of activity and attention (QbTest) on diagnostic and treatment decision-making in children and young people with ADHD-'Assessing QbTest Utility in ADHD' (AQUA): a randomised controlled trial. BMJ Open. 2014 Dec 1;4(12):e006838. doi: 10.1136/bmjopen-2014-006838. | |
| 25948406 |
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| Type | Date | Date Unknown |
|---|---|---|
| Release | Feb 5, 2019 | |
| Reset | May 3, 2019 |
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| Release Date | Unrelease Date | Unrelease Date Unknown | Reset Date | MCP Release Number |
|---|---|---|---|---|
| Feb 5, 2019 | May 3, 2019 |
| ID | Term |
|---|---|
| D001289 | Attention Deficit Disorder with Hyperactivity |
| D009043 | Motor Activity |
| ID | Term |
|---|---|
| D019958 | Attention Deficit and Disruptive Behavior Disorders |
| D065886 | Neurodevelopmental Disorders |
| D001523 | Mental Disorders |
| D001519 | Behavior |
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Stability in diagnosis and confidence between the QbO and QbB group measured as number of patients where the primary diagnosis (ADHD confirmed or excluded) was changed at their 6 month visit to the clinic.). |
| Up to 6 months |
| Medway NHS Foundation Trust |
| Gillingham |
| Kent |
| ME7 5NY |
| United Kingdom |
| Bridgewater Community Healthcare NHS Trust | Wigan | Lancashire | WN3 6PR | United Kingdom |
| Leicestershire Partnership Nhs Trust | Leicester | Leicestershire | LE5 0TD | United Kingdom |
| United Lincolnshire Hospitals NHS Trust | Lincoln | Lincolnshire | LN2 4AX | United Kingdom |
| Alder Hey Children's NHS Foundation Trust | Liverpool | Merseyside | L12 2AP | United Kingdom |
| Nottinghamshire Healthcare Nhs Trust | Nottingham | Nottinghamshire | NG3 6AA | United Kingdom |
| Nottingham University Hospitals Nhs Trust | Nottingham | Nottinghamshire | NG7 2UH | United Kingdom |
| Sussex Partnership NHS Foundation Trust | Worthing | Sussex | BN13 3EP | United Kingdom |
| Background |
| Hall CL, Walker GM, Valentine AZ. Correction. Protocol investigating the clinical utility of an objective measure of activity and attention (QbTest) on diagnostic and treatment decision-making in children and young people with ADHD - 'Assessing QbTest Utility in ADHD' (AQUA): a randomised controlled trial. BMJ Open. 2015 May 6;5(5):e006838corr1. doi: 10.1136/bmjopen-2014-006838corr1. No abstract available. |
| 29700813 | Derived | Hollis C, Hall CL, Guo B, James M, Boadu J, Groom MJ, Brown N, Kaylor-Hughes C, Moldavsky M, Valentine AZ, Walker GM, Daley D, Sayal K, Morriss R; the AQUA Trial Group. The impact of a computerised test of attention and activity (QbTest) on diagnostic decision-making in children and young people with suspected attention deficit hyperactivity disorder: single-blind randomised controlled trial. J Child Psychol Psychiatry. 2018 Dec;59(12):1298-1308. doi: 10.1111/jcpp.12921. Epub 2018 Apr 26. |
| 28183284 | Derived | Hall CL, Valentine AZ, Walker GM, Ball HM, Cogger H, Daley D, Groom MJ, Sayal K, Hollis C. Study of user experience of an objective test (QbTest) to aid ADHD assessment and medication management: a multi-methods approach. BMC Psychiatry. 2017 Feb 10;17(1):66. doi: 10.1186/s12888-017-1222-5. |