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| Name | Class |
|---|---|
| Abbott Nutrition | INDUSTRY |
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Patients with mechanical ventilation have shown improved weaning rates when enteral tube feeding high in EPA, GLA and antioxidants were fed to patients in the critical care setting.
LTAC Patients on chronic mechanical ventilation will have decreased days an mechanical ventilation, decreased mortality rates and decreased organ failure when fed an enteral product high in EPA, GLA and antioxidants compared to an isotonic high fiber enteral nutrition product.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Oxepa | Experimental | Other: Therapeutic nutrition with EPA, GLA and antioxidants. |
|
| Jevity 1.5 | Active Comparator | Other: Jevity 1.5 Complete Balanced Nutrition with Fiber . |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Oxepa | Other | Therapeutic nutrition with EPA, GLA< and antioxidants |
| |
| Measure | Description | Time Frame |
|---|---|---|
| Length of days on mechanical ventilation | 14 days from start of enteral feeding |
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Inclusion Criteria:
>18 years old with Respiratory failure on mechanical ventilation with failure to wean Diagnosis of ARDS (Acute respiratory Distress Syndrome) Bilateral infiltrates -
Exclusion Criteria:
History Of pulmonary fibrosis, Terminal illness/ malignancies, <28 day life expectancy, Hemodialysis, Active bleeding or bleeding disorder: DIC ( Disseminated intravascular Coagulation), Sickle Cell Anemia, Hemophilia Hemorrhagic or ischemic stroke, Liver failure, Head trauma with Glasgow coma scale score of <5, Immunosuppression: WBC(White Blood Cell Count) <5000, HIV positive, use of immunosuppressant drugs, Pregnancy, and Heart Failure with EF(Ejection Fraction) <35%
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| Name | Affiliation | Role |
|---|---|---|
| Basma Ricaurte, MD | Grace Hospital | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Grace Hospital | Recruiting | Cleveland | Ohio | 44111 | United States |
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| Jevity 1.5 |
| Other |
Complete balanced nutrition with a unique fiber blend |
|
| ID | Term |
|---|---|
| D055371 | Acute Lung Injury |
| ID | Term |
|---|---|
| D055370 | Lung Injury |
| D008171 | Lung Diseases |
| D012140 | Respiratory Tract Diseases |
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