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We hypothesize that it is feasible to integrate a program of Nutritional Care and Pychosocial Stimulation into the Community Clinics in Bangladesh and thereby improve malnourished children's growth and development after a year of intervention.
Over 200 million children <5 yrs do not reach their full potential due to poor nutrition and inadequate cognitive stimulation. Nutritional Care (NC) alone is insufficient to correct developmental deficit in malnourished children and psychosocial stimulation (PS) is also required.
Objectives:
Methods: The study consists of 3 different sub-studies:
Outcome variable: The main outcomes are children's language, mental and psychomotor development measured on Bayley-III. In addition we expect improvements in FCI and mother's child rearing knowledge and practices. We will also conduct cost analysis and based on the success indicators, cost per successful outcome will be calculated from total cost of intervention program.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Control | No Intervention | ||
| Psychosocial Stimulation and Nutritional Care | Experimental | Psychosocial Stimulation and Nutritional Care will be provided to malnourished children and their mothers every fortnight in the Community Clinics for one year. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Psychosocial Stimulation and Nutritional Care | Behavioral | Psychosocial Stimulation and Nutritional Care will be provided to malnourished children and their mothers every fortnight in the Community Clinics for one year. |
| Measure | Description | Time Frame |
|---|---|---|
| Cognitive, Language and Motor Composite Scores | The outcomes are measured on Bayley-III test. | 12 months |
| Anthropometry multiple measures, viz. Weight, length/height and head circumference | Children's weight, length/height and head circumference will be measured using standard methods. | 12 months |
| Behaviour | The outcome is measured using Wolke's behaviour ratings during the Bayley-III test. | 12 months |
| Measure | Description | Time Frame |
|---|---|---|
| Family Care Indicators | This outcome is measured by interviewing mothers of children about the quality of psychosocial stimulation at home. | 12 months |
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Inclusion Criteria:
Exclusion Criteria:
Children with above exclusion criteria or those whose parents do not wish to sign the consent form will not be included in the evaluation sample but if they wish they will receive the stimulation.
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| International Centre for Diarrhoeal Disease Research, Bangladesh | Dhaka | 1212 | Bangladesh |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 40230446 | Derived | Hossain SJ, Palmer T, Uddin Tipu SMM, Mehrin SF, Shiraji S, Hasan MI, Alam Bhuiyan MS, Salveen NE, Tofail F, Baker-Henningham H, Haghparast-Bidgoli H, Hamadani JD. Cost-effectiveness analysis of two integrated early childhood development programs into Bangladeshi primary health-care services. Lancet Reg Health Southeast Asia. 2025 Mar 28;35:100564. doi: 10.1016/j.lansea.2025.100564. eCollection 2025 Apr. | |
| 35783319 |
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| ID | Term |
|---|---|
| D008224 | Lymphoma, Follicular |
| D044342 | Malnutrition |
| ID | Term |
|---|---|
| D008228 | Lymphoma, Non-Hodgkin |
| D008223 | Lymphoma |
| D009370 | Neoplasms by Histologic Type |
| D009369 | Neoplasms |
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| ID | Term |
|---|---|
| D044623 | Nutrition Therapy |
| ID | Term |
|---|---|
| D013812 | Therapeutics |
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| Derived |
| Mehrin SF, Hasan MI, Tofail F, Shiraji S, Ridout D, Grantham-McGregor S, Hamadani JD, Baker-Henningham H. Integrating a Group-Based, Early Childhood Parenting Intervention Into Primary Health Care Services in Rural Bangladesh: A Cluster-Randomized Controlled Trial. Front Pediatr. 2022 Jun 10;10:886542. doi: 10.3389/fped.2022.886542. eCollection 2022. |
| 30784637 | Derived | Hamadani JD, Mehrin SF, Tofail F, Hasan MI, Huda SN, Baker-Henningham H, Ridout D, Grantham-McGregor S. Integrating an early childhood development programme into Bangladeshi primary health-care services: an open-label, cluster-randomised controlled trial. Lancet Glob Health. 2019 Mar;7(3):e366-e375. doi: 10.1016/S2214-109X(18)30535-7. |
| D008232 |
| Lymphoproliferative Disorders |
| D008206 | Lymphatic Diseases |
| D006425 | Hemic and Lymphatic Diseases |
| D007160 | Immunoproliferative Disorders |
| D007154 | Immune System Diseases |
| D009748 | Nutrition Disorders |
| D009750 | Nutritional and Metabolic Diseases |