Advancement of Modified Bubble CPAP

Advancement of Modified Bubble CPAP for the Use in Children in Low Resource Settings: A Study of Safety

This study proposes that modifying the current form of bCPAP by adjusting the nasal prongs to fit older children, will create a safe form of respiratory support that may help to decrease respiratory distress and thus mortality from pneumonia.

This study proposes that modifying the current form of bCPAP by adjusting the nasal prongs to fit older children, will create a safe form of respiratory support that may help to decrease respiratory distress and thus mortality from pneumonia. Children age 1 month (mo) to 5 years (y) admitted to Gulu Regional Referral Hospital in Gulu, Uganda with respiratory distress will be evaluated for use of the modified bCPAP device as treatment for their respiratory distress (in addition to their routine care, i.e. antibiotics, nutrition support)

Inclusion Criteria:

• Age 1mo-5y Hypoxia and/or respiratory distress Hypoxia- Oxygen saturation <92% despite 2LPM nasal cannula support Modified TAL's Respiratory Score >3

Exclusion Criteria:

• Pneumothorax
• Congenital lung disease
• Cyanotic heart disease
• Nasal trauma/facial injury/congenital anomaly (cleft) that makes bubble CPAP nasal interface unusable
• Nasal tissue injury
• Active nosebleed
• Recent abdominal surgery or significant abdominal distension
• Agonal respirations
• GCS <3
• Imminent death within the next 1-2hou