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| ID | Type | Description | Link |
|---|---|---|---|
| 12985 | Other Grant/Funding Number | Thrasher Research Fund |
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This study proposes that modifying the current form of bCPAP by adjusting the nasal prongs to fit older children, will create a safe form of respiratory support that may help to decrease respiratory distress and thus mortality from pneumonia.
This study proposes that modifying the current form of bCPAP by adjusting the nasal prongs to fit older children, will create a safe form of respiratory support that may help to decrease respiratory distress and thus mortality from pneumonia. Children age 1 month (mo) to 5 years (y) admitted to Gulu Regional Referral Hospital in Gulu, Uganda with respiratory distress will be evaluated for use of the modified bCPAP device as treatment for their respiratory distress (in addition to their routine care, i.e. antibiotics, nutrition support)
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Bubble CPAP | Experimental | Bubble CPAP for 28 days |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Bubble CPAP | Device | Respiratory assistance |
|
| Measure | Description | Time Frame |
|---|---|---|
| determine if a modified bCPAP device with an adapted nasal cannula can be used safely in children outside of the neonatal period | A composite of potential adverse events that could be attributable to bCPAP use. Adverse events such as nasal erosion, nosebleed, and aerophagia will be graded on a scale | 28 days |
| Measure | Description | Time Frame |
|---|---|---|
| show decreased mortality in patients treated with a modified bCPAP respiratory support device. | Comparison of historic mortality data for children admitted with respiratory distress to mortality rate seen during the study. Respiratory distress scores using the TAL score (18) will be recorded prior to therapy and throughout the hospital course | 28 days |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Ashley Bjorklund, MD | University of Minnesota | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Gulu Regional Referral Hospital | Gulu | Uganda |
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| ID | Term |
|---|---|
| D000860 | Hypoxia |
| D004417 | Dyspnea |
| ID | Term |
|---|---|
| D012818 | Signs and Symptoms, Respiratory |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D012120 | Respiration Disorders |
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| D012140 | Respiratory Tract Diseases |