Study of the Absorption, Metabolism, and Route of Elimination of a Novel Class of Anti-HIV 1 Drugs (BMS-955176) in Humans.

Pharmacokinetics and Metabolism of [14C] BMS-955176 in Healthy Male Subjects

The purpose of this study is to assess the pharmacokinetics (PK), metabolism, routes and extent of elimination, safety and tolerability of a single oral dose of [14C] BMS-955176 in healthy male subjects. There is no formal research hypothesis to be statistically tested for this study.

Inclusion Criteria:

• Healthy Male subjects
• Ages 18-50 years
• Body weight of at least 110 lbs (50kg)
• BMI of 18 to 32 kg/m^2
• non-smoking

Exclusion Criteria:

• Clinically significant diagnostic or therapeutic radiation exposure within the previous 12 months (eg serial X-ray or CAT scans, barium meals).
• gastrointestinal disease including gastrointestinal surgery
• constipation or irregular bowel movements