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Knowledge of the natural history and progression of macular holes is mainly limited to the studies from the pre-optical coherence tomography era. By observing macular holes preoperatively we are able to determine the extent of the preoperative macular hole progression.
At our institution macular holes are treated in an elective setting. The majority of macular holes undergo a 2-step sequence of phacoemulsification and intraocular lens implantation followed by vitrectomy.
We wish to observe the effect of time and cataract surgery on the progression of macular holes prior to vitrectomy.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Phakic eyes | Phakic eyes will be monitored with 4 preoperative optical coherence tomography scans as these patients will undergo phacoemulsification and intraocular lens implantation prior to their macular hole surgery | ||
| Pseudophakic eyes | Phakic eyes will be monitored with 2 preoperative optical coherence tomography scans as there is no surgical intervention prior to the macular hole treatment. |
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| Measure | Description | Time Frame |
|---|---|---|
| Macular hole Progression | Serial optical coherence tomography (OCT) measurements in the preoperative period. The size of macular hole is determined by measuring the macular hole minimal linear diameter (µm). Size and stage of macular hole is determined at primary evaluation at tertiary ophthalmic center. Initial scan is followed by pre-vitrectomy scan if patient is pseudophakic. Initial OCT scan is followed by pre- and postcataract as well as pre-vitrectomy OCT scan if patient is pseudophakic. | 3 months preoperative |
| Measure | Description | Time Frame |
|---|---|---|
| Early Treatment Diabetic Retinopathy Study (ETDRS) Visual Acuity | Visual acuity in ETDRS letters measured 3 month postoperatively | 3 months postoperative |
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Inclusion Criteria:
Exclusion Criteria:
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Tertiary Ophthalmic University Center
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| Name | Affiliation | Role |
|---|---|---|
| Morten la Cour, DMSc | Glostrup University Hospital, Copenhagen | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Glostrup Hospital, University of Copenhagen | Glostrup Municipality | 2600 | Denmark |
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| ID | Term |
|---|---|
| D012167 | Retinal Perforations |
| D018450 | Disease Progression |
| ID | Term |
|---|---|
| D012164 | Retinal Diseases |
| D005128 | Eye Diseases |
| D020969 | Disease Attributes |
| D010335 | Pathologic Processes |
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| D013568 |
| Pathological Conditions, Signs and Symptoms |