Influence of Moderate Inspired Oxygen Fraction (FiO2) and Protective Ventilation on Postoperative Pulmonary Complication

The purpose of this study is to determine the influence of moderate FiO2 and the lung protective ventilation on postoperative pulmonary complications following hepatic resection surgery.

Inclusion Criteria:

• ASA 1~2,Planned intrabdominal hepatic resection surgery;
• Expected duration 2 hours to 6 hours;
• Age 40 yr to 70 yr);
• BMI 18-26.9kg/m2
• Risk of postoperative pulmonary complications (Arozullah score ≥2);

Exclusion Criteria:

• Noninvasive ventilation in the last 30 days;
• Recent history of pneumonia, ALI/ARDS (in the last 30 days);
• History of pulmonary resection;
• History of neuromuscular disease;
• Child-Pugh>A grade；
• Patient refusal;