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| ID | Type | Description | Link |
|---|---|---|---|
| ARTHROPAT |
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This study aims to assess the effectiveness of two Physiotherapy treatments: one with manual therapy using joint traction, passive muscle stretching, and isometric exercise, active resisted and proprioception exercises; and other treatment with educational sessions and home exercises to improve the ROM, muscle strength and proprioception in patients with haemophilia and arthropathy of the knee.
Randomized trial with two treatment groups: one using joint traction, passive muscle stretching and isometric exercises, active resisted and proprioception exercises (group MT); and another with educational sessions and home exercises (group E); and a control group (group C).
The intervention was carried out during twelve weeks, performing evaluation before and after treatment, and six months of finalizing this. The treatment in MT group consisted of two sessions per week for one hour each, and the treatment in group E consisted of a session of 90 minute every two weeks, with exercises daily home. The control group (group C) did not receive any treatment. After the allocation to the groups, the composition was follows: MT group = 7; E group = 7; and control group = 7.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Manual Therapy group | Experimental | We employed joint traction, passive muscle stretching and isometric exercises, active resisted and proprioception exercises. The treatment in this group consisted of two sessions per week for one hour each. |
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| Educational gruop | Experimental | This group received educational sessions and home exercises. The exercises are aimed at improving quadriceps strength, flexibility, range of motion and knee proprioception. Each educational session of 90 minute every two weeks, with exercises daily home |
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| Control group | No Intervention | The control group (group C) did not receive any treatment. The patients of this group were assessed by the same reviewers and under the same conditions as the subjects of the two intervention groups. |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Manual Therapy | Other | 5 minutes. Thermotherapy shallow to 50 cm away from the knee. 15 minutes. Joint traction, grade I-II. Fixation of distal femur with cinch and manual fixation of proximal tibia. Patient in prone position and the traction is carried out in the submaximal ranges of flexion and extension. 10 minutes. Passive muscle stretching of quadriceps (within the limits of mobility), through compression muscle, passive muscle stretching and relaxation of muscle. 10 minutes. Isometric and resisted exercises of quadriceps, in submaximal ranges, of flexion and extension. 10 minutes. Proprioception exercises with unipodal support, with and without visual support, and posterior destabilization. 10 minutes. Local cryotherapy with ice pack. |
| Measure | Description | Time Frame |
|---|---|---|
| Changes in the range of movement (ROM) | Measurement of knee flexion and extension using a universal goniometer. Were taken as anatomical references, are indicated by Querol et al, using the reference method 0 to the mobile arm of the goniometer, as noted Norkin et al. | Screening visit (pretreatment assessment), postreatment evaluation (12 week) and follow up assessment (6 months after treatment) |
| Changes in quadriceps muscle circumference | Measurement in the thigh, in two thirds of the flow distance between the anterior superior iliac spine and the joint line of the knee, using a tape measure | Screening visit (pretreatment assessment), postreatment evaluation (12 week) and follow up assessment (6 months after treatment) |
| Changes in muscle strength of quadriceps | Measured by the rupture test for hemophilia patients (with a gradation of 0 to 5 points, with 0 indicating normal strength and 5 is the absence of muscle contraction). | Screening visit (pretreatment assessment), postreatment evaluation (12 week) and follow up assessment (6 months after treatment) |
| Changes in the perception of pain | Using the visual analog scale, VAS, consisting of a gradation of 0 to 10 points (from no pain to worst pain imaginable). | Screening visit (pretreatment assessment), postreatment evaluation (12 week) and follow up assessment (6 months after treatment) |
| Changes in the assessment of radiological joint deterioration | We use the Petterson scale which consists of 13 items (0 indicates a normal joint and joint deterioration 13 maximum). | Screening visit (pretreatment assessment), postreatment evaluation (12 week) and follow up assessment (6 months after treatment) |
| Measure | Description | Time Frame |
|---|---|---|
| Subjects' physical characteristics | Age of patient (years), Weight of patient (kg), Number of ankle haemarthrosis in previous year, Type of haemophilia (A or B), Severity of haemophilia (severe or moderate), Treatment (prophylaxis or on demand). | Screening visit (pretreatment assessment) |
| Changes in the frequency of knee hemarthrosis |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| RUBEN CUESTA-BARRIUSO, PhD | Universidad Católica San Antonio | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Universidad de Murcia | Murcia | Murcia | 30100 | Spain |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 27865846 | Derived | Cuesta-Barriuso R, Torres-Ortuno A, Nieto-Munuera J, Lopez-Pina JA. Effectiveness of an Educational Physiotherapy and Therapeutic Exercise Program in Adult Patients With Hemophilia: A Randomized Controlled Trial. Arch Phys Med Rehabil. 2017 May;98(5):841-848. doi: 10.1016/j.apmr.2016.10.014. Epub 2016 Nov 16. |
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| Type | Date | Date Unknown |
|---|---|---|
| Release | Oct 7, 2015 | |
| Reset | Nov 13, 2015 | |
| Release | Jun 29, 2016 | |
| Reset | Aug 12, 2016 | |
| Release | Aug 26, 2016 | |
| Reset | Oct 18, 2016 | |
| Release | May 15, 2024 | |
| Reset | Sep 18, 2024 |
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| Release Date | Unrelease Date | Unrelease Date Unknown | Reset Date | MCP Release Number |
|---|---|---|---|---|
| Oct 7, 2015 | Nov 13, 2015 | |||
| Jun 29, 2016 |
| ID | Term |
|---|---|
| D007592 | Joint Diseases |
| D006467 | Hemophilia A |
| ID | Term |
|---|---|
| D009140 | Musculoskeletal Diseases |
| D025861 | Blood Coagulation Disorders, Inherited |
| D001778 | Blood Coagulation Disorders |
| D006402 | Hematologic Diseases |
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| ID | Term |
|---|---|
| D026201 | Musculoskeletal Manipulations |
| ID | Term |
|---|---|
| D000529 | Complementary Therapies |
| D013812 | Therapeutics |
| D026741 | Physical Therapy Modalities |
| D012046 | Rehabilitation |
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| Educational Physiotherapy | Other |
|
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Evaluation of knee bleeding before, during and after physiotherapy treatment. Hemarthrosis must be diagnosed clinically. |
| Screening visit (pretreatment assessment), postreatment evaluation (12 week) and follow up assessment (6 months after treatment) |
| Aug 12, 2016 |
| Aug 26, 2016 | Oct 18, 2016 |
| May 15, 2024 | Sep 18, 2024 |
| D006425 | Hemic and Lymphatic Diseases |
| D020147 | Coagulation Protein Disorders |
| D006474 | Hemorrhagic Disorders |
| D030342 | Genetic Diseases, Inborn |
| D009358 | Congenital, Hereditary, and Neonatal Diseases and Abnormalities |