BOTOX® in the Treatment of Crow's Feet Lines in China

This study will evaluate the safety and efficacy of BOTOX® (botulinum toxin Type A) compared with placebo in patients with moderate to severe crow's feet lines (lateral canthal lines).

Inclusion Criteria:

-Moderate to severe Crow's Feet Lines.

Exclusion Criteria:

• Current or previous treatment with botulinum toxin of any serotype for any condition within the last year
• Diagnosis of myasthenia gravis, Eaton-Lambert syndrome, amyotrophic lateral sclerosis
• Facial laser or light treatment, microdermabrasion or chemical peels within 3 months
• Radio frequency laser treatments, phototherapy, blepharoplasty, brow-lift or related procedure, permanent make-up, oral retinoid therapy or treatment with non-permanent soft tissue fillers within 1 year
• Any medium-depth or deep facial peels within 5 years
• Periorbital surgery, face-lift, mid facial or periorbital treatment with permanent soft tissue fillers, synthetic implants or autologous fat transplant.