Comparative Bioavailability Study of Film-coated Tablet and Granule Formulations of RG1662

A Randomized, Open-Label, Four Period, Four-Treatment Crossover Study to Investigate the Comparative Bioavailability of Film-Coated Tablet and Granule Formulations of RG1662 Under Fed and Fasted Conditions in Healthy Volunteers

This study will compare the pharmacokinetic performance of film-coated tablet and granule formulations of RG1662 under fed and fasted conditions in healthy volunteers. A randomized, four-period, four-treatment crossover design is used. In each period, each volunteer will receive a single oral dose of the tablet or granule formulation either with or without food.

Inclusion Criteria:

• Male or female volunteers, 18 to 60 years of age, inclusive

Exclusion Criteria:

• A history of epilepsy, convulsions or significant head injury
• Any other clinically relevant abnormalities, concomitant diseases or ongoing medical conditions