Probiotic Supplementation to Improve the GUT Microbiota of Very Low Birth Weight Preterm, a Pilot Study

Probiotic Supplementation to Improve the GUT Microbiota of Very Low Birth Weight, a Pilot Study

This pilot trial is designed to investigate the benefits of the use of probiotics in GUT microbiota development and/or immunological biomarkers and how this can be related with the clinical status of very low birth weight preterms during their first weeks of life at the neonatal intensive care unit(NICU).

This pilot trial is designed to investigate the benefits of the use of mixtures of probiotics isolated from human milk in GUT microbiota development and/or immunological biomarkers. Furthermore, the relationship between evaluated parameters and the clinical status of very low birth weight preterms during their first weeks of life at the NICU will be analysed.

Inclusion Criteria:

• preterm infants with birth weight less than one thousand and three hundred grammes
• preterm infants with gestational age less than 29 weeks

Exclusion Criteria:

• mayor malformations
• chromosomopathies
• congenital infections
• non parental consent