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| Name | Class |
|---|---|
| Patient-Centered Outcomes Research Institute | OTHER |
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Our long-term goal is to integrate non-small cell lung cancer patient treatment preferences into clinical treatment planning.
The following specific aims are proposed:
Aim 1: Determine whether individual patients' preferences, characteristics, and treatment experiences affect the definition of treatment success.
Aim 2: Determine how to best predict real-life patients' treatment choices based on patients' preferences of adverse events.
Aim 3: Determine whether physicians are likely to change their oncologic clinical practice after receiving a detailed communication of their patients' preferences of adverse events.
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| Measure | Description | Time Frame |
|---|---|---|
| Patient-defined "treatment success" | In advanced stage NSCLC patients does patient-defined "treatment success" differ when both survival and patient preferences of adverse events are accounted for, compared to when success is measured solely by survival? And does it also differ based on individual patient characteristics? | Baseline |
| Patients' will to experience adverse events | Will the serious adverse events that an advanced stage NSCLC patient is willing to experience as part of his/her treatment differ after a real-life treatment experience, compared to before treatment? | Baseline |
| Measure | Description | Time Frame |
|---|---|---|
| Summary score derived from patient preferences of adverse events | In advanced stage NSCLC patients, is a summary score derived from patient preferences of adverse events comparable to a real-life treatment scenario? | Up to three months |
| Measure | Description | Time Frame |
|---|---|---|
| Physicians' will to select a treatment | Are physicians treating NSCLC patients more likely to select a treatment that matches patients' drug choices when provided standardized, detailed information on patients' preferences of adverse events compared to when they follow regular clinical practice? | Two years |
Inclusion Criteria:
Willing and able to provide consent
Greater than or equal to 19 years of age
Diagnosed with stage IV non-small cell lung cancer (NSCLC)
Able to understand spoken English
Eligible to undergo chemotherapy for stage IV NSCLC, to include, but not limited to, those who:
Exclusion Criteria:
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Newly diagnosed advanced stage non-small cell lung cancer patients with age > 19 years.
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| KM Munirul Islam, MD, PhD | Contact | 402-559-8283 | kmislam@unmc.edu |
| Name | Affiliation | Role |
|---|---|---|
| KM Munirul Islam, MD, PhD | University of Nebraska | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Moffitt Cancer Center | Recruiting | Tampa | Florida | 33612-9416 | United States |
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| Label | URL |
|---|---|
| Patient Centered Outcomes Research Institute | View source |
| University of Nebraska Medical Center | View source |
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| Type | Date | Date Unknown |
|---|---|---|
| Release | Feb 28, 2017 | |
| Reset | Apr 11, 2017 | |
| Release | Dec 11, 2017 |
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| Kansas City VA Medical Center | Recruiting | Kansas City | Missouri | 64128 | United States |
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| Saint Francis Cancer Treatment Center | Recruiting | Grand Island | Nebraska | 68803 | United States |
| Southeast Nebraska Cancer center | Recruiting | Lincoln | Nebraska | 68510 | United States |
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| Callahan Cancer Center of Great Plains Regional Medical Center | Recruiting | North Platte | Nebraska | 69101 | United States |
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| Nebraska-Western Iowa (NWI) VA Health Care System | Recruiting | Omaha | Nebraska | 68105 | United States |
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| University of Nebraska Medical Center | Recruiting | Omaha | Nebraska | 68198 | United States |
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| Avera Cancer Institute | Recruiting | Sioux Falls | South Dakota | 57105 | United States |
| Reset | Oct 5, 2018 |
| Release | Feb 1, 2024 |
| Reset | Jul 19, 2024 |
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| Release Date | Unrelease Date | Unrelease Date Unknown | Reset Date | MCP Release Number |
|---|---|---|---|---|
| Feb 28, 2017 | Apr 11, 2017 | |||
| Dec 11, 2017 | Oct 5, 2018 | |||
| Feb 1, 2024 | Jul 19, 2024 |
| ID | Term |
|---|---|
| D003075 | Coitus |
| ID | Term |
|---|---|
| D012725 | Sexual Behavior |
| D001519 | Behavior |
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