Antibiotic Irrigation for Pancreatoduodenectomy

Routine Antibiotic Irrigation in Patients Undergoing Pancreatoduodenectomy to Reduce Infection and Fistula Rates

The purpose of this study is to determine if the routine use of antibiotic irrigation during pancreas surgery (Whipple procedure) will decrease superficial and organ space infections.

The primary aim of this study is to test the efficacy of routine antibiotic irrigation in reducing superficial and organ space infections among patients undergoing pancreatoduodenectomy.

Inclusion Criteria:

• At least 18 years of age and older;
• Open pancreatoduodenectomy for any diagnosis

Exclusion Criteria:

• Pregnant;
• Prisoners;
• Patients undergoing concomitant colectomy;
• Antibiotic allergy to study medication;
• Serum creatinine > 2.0;
• Unable to provide informed consent