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| ID | Type | Description | Link |
|---|---|---|---|
| AinShamsMH | Other Identifier | AinShamsMH |
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A randomized controlled study comparing the effect of administration of 1 gm ceftriaxone in elective cesarean section 30-60 min before skin incision versus after cord clamping.
comparing the effect of administration of 1 gm ceftriaxone in elective cesarean section 30-60 min before skin incision versus after cord clamping.on post-cesarean section infection(wound infection as a primary outcome)
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Group A ceftriaxone after cord clamping | Experimental | 165 patients pregnant at 37weeks or more undergoing elective cesarean section randomly distributed to receive 1 gm. ceftriaxone via l intravenous infusion single dose after cord clamping. |
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| Group B ceftriaxone before skin incision | Active Comparator | 165 patients pregnant at 37weeks or more undergoing elective cesarean section randomly distributed to receive 1 gm. ceftriaxone vial intravenous infusion single dose 30-60 minutes before skin incision. |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| ceftriaxone 1gm for intravenous infusion | Drug | Patients undergoing elective cesarean section with Gestational age 37 weeks or more. comparing the effect of administration of 1 gm ceftriaxone in elective cesarean section 30-60 min before skin incision versus after cord clamping.on post-cesarean section infection(wound infection as a primary outcome) |
| Measure | Description | Time Frame |
|---|---|---|
| The primary outcome is the rate of post cesarean section surgical site infection. | postoperative assessment of SSI. Patients will be followed up at 48-72 hours postoperative, at 7th days (skin suture removal) and at 6 weeks (contraception application).all patients will be contacted by telephone and interviewed. They will be rescheduled for a clinic visit if they reported signs and symptoms of wound infection (purulent discharge or erythema >1 cm in diameter, induration of the incision site and fever). | administration of 1gm ceftriaxone prophylaxis for elective cs and follow up surgical site infection till 40 days |
| Measure | Description | Time Frame |
|---|---|---|
| other post cesarean section maternal and neonatal infection |
| follow up ofother post cesarean section maternal and neonatal infection till 40 days of delivery |
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Inclusion Criteria:
Exclusion Criteria:
3) Morbid obesity (BMI>30)
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| Name | Affiliation | Role |
|---|---|---|
| Amr AH Helmy, MD | Ain Shams Maternity Hospital | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Antibiotic Prophylaxis for Elective Cesarean Section | Cairo | +20 | Egypt |
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| ID | Term |
|---|---|
| D007262 | Infusions, Intravenous |
| ID | Term |
|---|---|
| D061605 | Administration, Intravenous |
| D004333 | Drug Administration Routes |
| D004358 | Drug Therapy |
| D013812 | Therapeutics |
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| D007263 |
| Infusions, Parenteral |