Computerized Cognitive Behavioral Therapy and Electroconvulsive Therapy

Evaluating the Feasibility and Efficacy of Computerized Cognitive Behavioral Therapy in Prolonging the Antidepressant Effects of Electroconvulsive Therapy

In an open-label feasibility study, fifteen will be recruited to participate in the study from among those who have already chosen of their own accord to undergo ECT (standard of care) at Yale Psychiatric Hospital for treatment of a depressive episode. These patients will receive computer-assisted cognitive behavior therapy (CCBT).

Inclusion Criteria:

• 18-75 years old
• meet DSM-5 criteria for depressive episodes
• able to use a computer

Exclusion Criteria:

• diagnosis of an axis II (personality disorder)
• active suicidal thoughts with a plan
• current substance use disorder
• non-affective psychosis
• prior treatment with ECT in the past 6 months
• CBT treatment in the past 12 months
• dementia
• delirium or another other neurological or mental disease that might affect cognition or the ability to meaningfully participate in computerized CBT