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| Name | Class |
|---|---|
| Universidade Federal do Triangulo Mineiro | OTHER |
| Coordenação de Aperfeiçoamento de Pessoal de NÃvel Superior. | OTHER_GOV |
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Obesity is a growing problem worldwide and its prevention has become one of the leading priorities for the World Health Organisation. Obesity results from chronic imbalance between energy intake and energy expenditure. Although early prevention of obesity is preferable, surgical treatment is often required for severely obese people.
Bariatric surgery has been shown to be the most effective therapy for severe obesity. Weight loss following bariatric surgery results in significant improvements in coexisting comorbidities, such as diabetes and hypertension but there is controversy whether bariatric surgery also improves aerobic capacity.
The purpose of this study is to investigate the effects of bariatric surgery on cardiopulmonary function and on daily physical activity. It is hypothesized that bariatric surgery will improve aerobic capacity and result in beneficial lifestyle changes from sedentary to more active.
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| Measure | Description | Time Frame |
|---|---|---|
| Cardiorespiratory function assessed by peak oxygen consumption (VO2peak) | One to two weeks before surgery and six months after surgery |
| Measure | Description | Time Frame |
|---|---|---|
| Lung function | Lung function will be assessed by spirometry and body plethysmography | One to two weeks before surgery and six months after surgery |
| Heart function | Echocardiography will be performed to assess heart function. |
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Inclusion Criteria:
Exclusion Criteria:
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Patients with scheduled bariatric surgery at St George's Healthcare NHS Trust.
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Dimitra Nikoletou, PhD | Contact | +44 20 8725 5647 | dinikole@sgul.ac.uk |
| Name | Affiliation | Role |
|---|---|---|
| Marcia S Volpe | Universidade Federal Triangulo Mineiro | Principal Investigator |
| Dimitra Nikoletou | Kingston University and St George's University of London | Study Chair |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| St George's Healthcare NHS Trust | Recruiting | London | SW17 0RE | United Kingdom |
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| ID | Term |
|---|---|
| D009765 | Obesity |
| D009043 | Motor Activity |
| ID | Term |
|---|---|
| D050177 | Overweight |
| D044343 | Overnutrition |
| D009748 | Nutrition Disorders |
| D009750 | Nutritional and Metabolic Diseases |
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| One to two weeks before surgery and six months after surgery |
| Inspiratory muscle strength | Maximal inspiratory pressure and sniff nasal pressure will be recorded. | One to two weeks before surgery and six months after surgery |
| Peripheral muscle strength | Maximum isometric strength of hand/ forearm, quadriceps and hip flexors muscles will be evaluated | One to two weeks before surgery and six months after surgery |
| Free living sedentary and physical activity times | Daily physical activity habits will be assessed by an accelerometer and International Physical Activity Questionnaire: Long (IPAQ-Long). Participants will be required to wear the accelerometer for four consecutive days during the two study points. | One to two weeks before surgery and six months after surgery |
| Marcus Reddy |
| St George's Healthcare NHS Trust |
| Study Director |
| D001835 |
| Body Weight |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D001519 | Behavior |