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Since introduction in 1989, propofol has gained wide acceptance for sedation during endoscopic procedures. The optimal sedation drug during esophagogastroendoscopy (EGD) is not established. Midazolam and propofol are used for sedation drug. Balanced propofol sedation (BPS) refers to the administration of an opiate, a benzodiazepine, and propofol. In this study, the investigators want to compare the patient satisfaction with EGD following balanced propofol sedation (BPS) versus propofol sedation alone.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| balanced propofol group | Experimental |
| |
| propofol alone group | Active Comparator |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Midazolam + propofol | Drug | Midazolam and propofol are used for sedation drug. Balanced propofol sedation (BPS) refers to the administration of an opiate, a benzodiazepine, and propofol. |
| Measure | Description | Time Frame |
|---|---|---|
| visual analog scale | The patient satisfaction with EGD following balanced propofol sedation (BPS) versus propofol sedation alone | Within the 24 hours after EGD |
| Measure | Description | Time Frame |
|---|---|---|
| complications rates | The recovery time after EGD following balanced propofol sedation versus propofol sedation alone. The safety after EGD following balanced propofol sedation versus propofol sedation alone | Within the 1 hour after EGD |
| Measure | Description | Time Frame |
|---|---|---|
| complications rates | The safety after EGD following balanced propofol sedation versus propofol sedation alone | Within the 1 hour after EGD |
| total dose of the sedation drugs | The economy after EGD following balanced propofol sedation versus propofol sedation alone |
Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Yonsei university College of Medicine | Seoul | Seoul | 120-752 | South Korea |
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| ID | Term |
|---|---|
| D008874 | Midazolam |
| D015742 | Propofol |
| ID | Term |
|---|---|
| D001569 | Benzodiazepines |
| D001552 | Benzazepines |
| D006574 | Heterocyclic Compounds, 2-Ring |
| D000072471 | Heterocyclic Compounds, Fused-Ring |
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| propofol | Drug | propofol are used for sedation drug |
|
| Within the 1 hour after EGD |
| visual analog scale | The endoscopist's satisfaction with EGD following balanced propofol sedation (BPS) versus propofol sedation alone | Within the 1 hour after EGD |
| D006571 | Heterocyclic Compounds |
| D010636 | Phenols |
| D001555 | Benzene Derivatives |
| D006841 | Hydrocarbons, Aromatic |
| D006844 | Hydrocarbons, Cyclic |
| D006838 | Hydrocarbons |
| D009930 | Organic Chemicals |