Reduction the Duration of Antibiotic Therapy in the Elderly (PROPAGE)

Reduction of the Duration of Antibiotic Guided by Procalcitonin in Infections Lungs of Hospitalized Elderly: a Randomized

The main objective is to evaluate the interest of the repeated measurement of procalcitonin in patients with pulmonary infection to reduce the duration of antibiotic therapy in comparison with a conventional clinical strategy.

Inclusion Criteria:

• Age ≥ 80 years
• Started antibiotics for a chest infection
• Procalcitonin performed J0 antibiotic treatment
• Person affiliated to the social security

Exclusion Criteria:

• Patients with a documented infection with germs after Listeria spp, Legionella pneumophilia, Mycobacterium tuberculosis
• Patients with a documented infection with a virus or parasite (eg hemorrhagic fever, malaria)
• Patients with endovascular infection associated (endocarditis, pacemaker. Intravascular catheter)
• Patients with lung abscess associated upon entry Patients with a chronic infection associated
• Patients with severe immunosuppression (HIV or transplant)
• Palliative patient
• Death within 24 hours of admission to nursing units.
• Presence of antibiotic treatment for chronic infection.
• Patient under guardianship, curatorship or any other administrative or judicial action or deprivation of the right or freedom
• Patients hospitalized without their consent