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| Name | Class |
|---|---|
| University of Manchester | OTHER |
| Dow University of Health Sciences | OTHER |
| Abbasi Shaheed Hospital | OTHER |
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Aim:
To assess the feasibility of culturally adapted Family Intervention for Psychosis.
Design:
Randomized Control Trial
Setting:
psychiatric department of different hospitals
Participants:
A total of 36 caregivers of Psychosis patients will be randomized to psychological Intervention and treatment as usual arm.
Intervention:
Culturally Adapted Family Intervention for Psychosis
Outcome measure:
Positive and Negative syndrome scale (PANSS) Experience of care -giving inventory(ECI) Care Well-Being & Support(CWS)
The purpose of the study is to test the feasibility of culturally adaptive family intervention for Psychosis
Primary Objective :
the investigators will conduct a feasibility pilot study to test whether Pakistani families offered the intervention will want to receive it. The Participants will be recruited from psychiatric department of different hospitals. They will be randomly divided into two groups; intervention group and treatment-as-usual group. A total of thirty six participants will be recruited in the pilot study and divided equally into two arms. This will ensure that, even after loss to follow-up, we will have at least 12 subjects per group for analysis (FDA guidance http://www.fda.gov/cder/guidance/5356fnl.pdf).Randomization will be carried out by the on offsite statistician. This will provide a reliable geographically remote service. For intervention group ten sessions of family intervention will be provided by trained research clinician during the period of three months. Relatives of Patients in the treatment as usual (TAU) group will be given details of intervention at the end of the study and interested families will be offered family intervention
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Family Intervention | Experimental | Culturally Adapted Family intervention for Psychosis Sessions will be offered weekly basis |
|
| Control | No Intervention | Caregiver ' s Patients who will be randomized to the "treatment as usual" arm will receive routine care |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Family intervention | Behavioral | This 10 session Multi-modal Psychosocial Intervention will include a supportive component, an educational component, psychosocial component |
|
| Measure | Description | Time Frame |
|---|---|---|
| Positive and Negative syndrome scale (PANSS) | The PANSS is a structured clinical interview consisting of 30 items designed to assess severity of symptoms over the past week on a 7-point scale. | six months |
| Experience of Care-giving inventory(ECI) | Commonly apply to persons who care for relative or friends With a serious mental illness | six months |
| Carer Wel-Being & Support(CWS) | A questionnaire for carers of people with a mental Health problem | six months |
| Measure | Description | Time Frame |
|---|---|---|
| Family Questionnaire(FQ) | Find out the problem of caregiver for relative or friends With a serious mental illness. | six months |
| Insight rating scale | Assesses Improvement in insight |
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Inclusion Criteria:
Exclusion Criteria:
Severe drug or alcohol problem (i.e., those who fulfill the criteria for dependence according to ICD10 RDC).
Unstable residential arrangements such that the likelihood of being available for the duration of the trial is low.
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| Name | Affiliation | Role |
|---|---|---|
| Nusrat Husain, MD | Pakistan Institute of Learning and Living, University of Manchester | Principal Investigator |
| Imran Chaudhry, MD | University of Manchester | Principal Investigator |
| Farooq Naeem, MRCPsych | Pakistan Institute of Learning and Living, University of Southampton | Principal Investigator |
| Raza Ur Rehman, FCPS | Dow University of Health Sciences | Principal Investigator |
| Ajmal kazm | Pakistan Institute of Living and Learning | Principal Investigator |
| Munir Hamirani, FCPS | Abbasi Shaheed Hospital | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Dow University of Health Sciences | Karachi | Sindh | Pakistan |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 32930011 | Derived | Husain MO, Khoso AB, Renwick L, Kiran T, Saeed S, Lane S, Naeem F, Chaudhry IB, Husain N. Culturally adapted family intervention for schizophrenia in Pakistan: a feasibility study. Int J Psychiatry Clin Pract. 2021 Sep;25(3):258-267. doi: 10.1080/13651501.2020.1819332. Epub 2020 Sep 15. |
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| ID | Term |
|---|---|
| D011618 | Psychotic Disorders |
| D003117 | Color Vision Defects |
| ID | Term |
|---|---|
| D019967 | Schizophrenia Spectrum and Other Psychotic Disorders |
| D001523 | Mental Disorders |
| D014786 | Vision Disorders |
| D012678 | Sensation Disorders |
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| ID | Term |
|---|---|
| D000083626 | Psychosocial Intervention |
| ID | Term |
|---|---|
| D011613 | Psychotherapy |
| D004191 | Behavioral Disciplines and Activities |
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|
| six months |
| Calgary Depression Scale for Schizophrenia | This is a nine-item scale developed by Addington et al. to assess depression in schizophrenia | six months |
| Short Explanatory Model Interview | used to elicit beliefs of mental illness | six months |
| D009461 | Neurologic Manifestations |
| D009422 | Nervous System Diseases |
| D000077765 | Cone Dystrophy |
| D015785 | Eye Diseases, Hereditary |
| D005128 | Eye Diseases |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |