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| ID | Type | Description | Link |
|---|---|---|---|
| 2012-A01053-40 | Other Identifier | ID-RCB |
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the aim of the study is to determine if Spontaneous Ventilation with Positive Pressure Ventilation (PPV) preoxygenation allows a longer non hypoxemic apnea time during panendoscopy compared to spontaneous breathing preoxygenation.
the hypothesis is PPV extends the residual functional capacity of lung so it provides more oxygen during apnea.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| positive pressure ventilation | Experimental | Positive Pressure Ventilation with a 4 cmH2O inhale pressure, a positive end-expiratory pressure of 4 cm H2O, a trigger 2, an inspiratory slope of 0, an inhaled oxygen fraction of 100% administered at a 10 L / min flow. |
|
| Oxygenation with simple breathing mask | Active Comparator | spontaneously breathing preoxygenation with adapted face mask, to restrict leakage, at 10L/min oxygen, with inhaled fraction of 100% and a 2 L balloon volume. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| positive pressure ventilation | Device | Positive Pressure Ventilation with a 4 cmH2O inhale pressure, a positive end-expiratory pressure of 4 cm H2O, a trigger 2, an inspiratory slope of 0, an inhaled oxygen fraction of 100% administered at a 10 L / min flow. |
| Measure | Description | Time Frame |
|---|---|---|
| non hypoxemic apnea time | time the oxygen saturation is going down to 90% during apnea | up to 5 minutes after stopping oxygenation |
| Measure | Description | Time Frame |
|---|---|---|
| surgical laryngoscopy frequency | number of stopped surgical laryngoscopy because of a low oxygen saturation under 90% with necessity to ventilate the patients during apnea | up to 15 minutes after stopping oxygenation |
| preoxygenation time |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Osama ABOU ARAB, MD | CHU Amiens | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| CHU Amiens | Amiens | 80000 | France |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 26716862 | Result | Abou-Arab O, Guinot PG, Dimov E, Diouf M, de Broca B, Biet A, Zaatar R, Bernard E, Dupont H, Lorne E. Low-positive pressure ventilation improves non-hypoxaemic apnoea tolerance during ear, nose and throat pan-endoscopy: A randomised controlled trial. Eur J Anaesthesiol. 2016 Apr;33(4):269-74. doi: 10.1097/EJA.0000000000000394. |
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| ID | Term |
|---|---|
| D011175 | Positive-Pressure Respiration |
| D063087 | Noninvasive Ventilation |
| ID | Term |
|---|---|
| D012121 | Respiration, Artificial |
| D058109 | Airway Management |
| D013812 | Therapeutics |
| D012138 | Respiratory Therapy |
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|
| Oxygenation with simple breathing mask | Procedure | Spontaneously breathing preoxygenation with adapted face mask, to restrict leakage, at 10L/min oxygen, with inhaled fraction of 100% and a 2 L balloon volume. |
|
time to reach expired oxygen fraction to 90%
| up to 10 min after the start of oxygenation |