The Effects of Intraoperative Dexmedetomidine Infusion on Postoperative Bowel Movement in Patients Undergoing Laparoscopic Gastrectomy

The investigators hypothesized that sympatholytic effect of dexmedetomidine would attenuate the hemodynamic instability and decrease in the splanchnic blood flow caused by pneumoperitoneum during laparoscopic surgery. This study is to investigate the effect of intraoperative dexmedetomidine infusion on postoperative bowel movement in patients undergoing laparoscopic gastrectomy.

Inclusion Criteria:

• patient between 20 and 65 of age with ASA physical status Ⅰ-Ⅲ
• gastric cancer patient undergoing laparoscopic gastrectomy

Exclusion Criteria:

• ASA physical status Ⅳ
• bradycardia (< 60 bpm), arrhythmia
• uncompensated heart failure
• hepatic failure (Child-Pugh score B 이상)
• renal failure (eGFR MDRD < 60 ml/min/1.73m2)