Anxiety disorders are common and impairing. Although exposure therapy is one of the most effective treatments for anxiety, some individuals do not fully respond to treatment, and these individual differences are not well understood. Exposure therapy involves repeated, deliberate, safe engagement with a feared stimulus without the feared outcome occurring. This treatment is thought to work through a type of emotional learning called fear extinction. This study aims to look at links between fear extinction learning and exposure success, with the overall goal of better understanding who is likely to respond best to exposure therapy and why.

Inclusion Criteria:

• Score of at least 20 on the PRCS
• Age 18-55
• English fluency

Exclusion Criteria:

• Psychotropic medication use in the past 4 weeks
• Past experience with exposure based therapy
• History of bipolar disorder, psychotic disorder, or substance dependence
• Current major depressive disorder of greater than moderate severity (defined as a score on the 9 item Patient Health Questionnaire of greater than 14)
• Clinically significant suicidal or homicidal ideation
• Non-removable ferrous metal
• Current significant neurological conditions
• History of loss of consciousness greater than 5 minutes duration
• Pregnant
• Claustrophobic

Community sample