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Transversus abdominis plane block (TAPB) has emerged as a safe and effective regional anesthesia technique for providing postoperative lower abdominal analgesia. Complications associated with TAPB are very rare and pose a lower overall risk to the patient receiving a TAPB versus a caudal block, which is considered the gold standard for pediatric lower abdominal regional anesthesia. Our study hypothesis was that TAPB would be equivalent to caudal block initially in providing postoperative pain control but would show improved pain relief beyond the anticipated caudal duration.
The study design was a double-blinded randomized controlled trial. A minimum of 44 children between the ages of 1 and 9 undergoing bilateral ureteral reimplantation surgery through a low transverse incision will be enrolled. Narcotic requirement, pain scores (FLACC/FACES), episodes of nausea/vomiting, and anti-spasmodic requirement will be recorded in the PACU and at 6 hour intervals through 24 hours from the time of the block placement.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Transversus Abdominis Plane Block | Experimental | Transversus Abdominis Plane Block TAPB Ultrasound guided TAPB |
|
| Caudal Epidural Block | Experimental | Caudal Epidural Block Caudal Block Neuraxial Block Ultrasound Guided Caudal Block |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Caudal Epidural | Procedure | Ultrasound Guided Caudal Block |
| |
| Measure | Description | Time Frame |
|---|---|---|
| Narcotic requirement | Narcotic requirement was recorded at 24 hours from the time of the block placement. | 24 hours post intervention |
| Measure | Description | Time Frame |
|---|---|---|
| episodes of nausea/vomiting | Episodes of nausea/vomiting were recorded at 24 hours from the time of the block placement. | 24 hours |
| anti-spasmodic requirement | Anti-spasmodic requirement were recorded at 24 hours from the time of the block placement. |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Robert B Bryskin, MD | Nemours Children's Clinic | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Wolfson Children's Hospital, Baptist Medical Center- Downtown, 800 Prudential Drive | Jacksonville | Florida | 32207 | United States |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 16094063 | Background | Tripi PA, Palmer JS, Thomas S, Elder JS. Clonidine increases duration of bupivacaine caudal analgesia for ureteroneocystostomy: a double-blind prospective trial. J Urol. 2005 Sep;174(3):1081-3. doi: 10.1097/01.ju.0000169138.90628.b9. | |
| 17513626 | Background | Vetter TR, Carvallo D, Johnson JL, Mazurek MS, Presson RG Jr. A comparison of single-dose caudal clonidine, morphine, or hydromorphone combined with ropivacaine in pediatric patients undergoing ureteral reimplantation. Anesth Analg. 2007 Jun;104(6):1356-63, table of contents. doi: 10.1213/01.ane.0000261521.52562.de. |
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| ID | Term |
|---|---|
| D000763 | Anesthesia, Caudal |
| ID | Term |
|---|---|
| D000767 | Anesthesia, Epidural |
| D000765 | Anesthesia, Conduction |
| D000758 | Anesthesia |
| D000760 | Anesthesia and Analgesia |
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| Transversus Abdominis Plane Block |
| Procedure |
Ultrasound Guided Transversus Abdominis Plane Block |
|
| 24 hours post intervention |
| Pain Scores | Pain scores (FLACC/FACES) were recorded at 24 hours from the time of the block placement | 24 hours post intervention |
| 25902326 | Derived | Bryskin RB, Londergan B, Wheatley R, Heng R, Lewis M, Barraza M, Mercer E, Ye G. Transversus Abdominis Plane Block Versus Caudal Epidural for Lower Abdominal Surgery in Children: A Double-Blinded Randomized Controlled Trial. Anesth Analg. 2015 Aug;121(2):471-8. doi: 10.1213/ANE.0000000000000779. |