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During pregnancy nutrition demands change and the pregnant woman needs to adjust her food intake and take into consideration the corrected daily recommendations for micro and macro nutrients. Pregnant woman tend to suffer from hyperemesis and this affects their food choice.
Amongst pregnant women with Diabetes the glucose balance is extremely important during pregnancy. Glucose balance is a result of correct nutrition and an exact amount of insulin. This delicate balance requires from the pregnant women an ability to perform correct carbohydrate count.
Hyperglycemia has already been proven to affect the fetus and the neonatal outcomes. Hypoglycemia may also have a negative effect but the main danger is immediate harm to the mother and therefore to the fetus. For those reasons glucose balance is crucial and demands delicate synchronization of nutrition and insulin therapy.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Type 1 and Type 2 Diabetes | pregnant women which have a known condition of type 1 or type 2 diabetes | ||
| Gestational diabetes | pregnant women which have developed Gestational diabetes | ||
| Control group | Pregnant women whom do not suffer from any altered glucose metabolism |
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| Measure | Description | Time Frame |
|---|---|---|
| Post prandial blood glucose levels | For every time point blood glucose will be analyzed for blood glucose and for Insulin and C-peptide for the control group | The outcome will be measured at various time points during a 120 min OGTT: Fasting, 30, 60, 90 and 120 min |
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Inclusion Criteria:
Exclusion Criteria:
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Women perticapting in this study will be from the high risk pregnancy clinic of hadassah Ein Kerem.
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Uriel Elchalal, MD | Contact | uriel@hadassah.org.il |
| Name | Affiliation | Role |
|---|---|---|
| Ram Weiss, Md PhD | Hebrew Universtity | Principal Investigator |
| Karen J Hershkop, PhD | Hebrew University | Principal Investigator |
| Limor Marko, MSc |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Hadassah Ein Kerem | Recruiting | Jerusalem | 91120 | Israel |
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| ID | Term |
|---|---|
| D003922 | Diabetes Mellitus, Type 1 |
| D003924 | Diabetes Mellitus, Type 2 |
| D016640 | Diabetes, Gestational |
| ID | Term |
|---|---|
| D003920 | Diabetes Mellitus |
| D044882 | Glucose Metabolism Disorders |
| D008659 | Metabolic Diseases |
| D009750 | Nutritional and Metabolic Diseases |
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| Hebrew University |
| Principal Investigator |
| D004700 | Endocrine System Diseases |
| D001327 | Autoimmune Diseases |
| D007154 | Immune System Diseases |
| D011248 | Pregnancy Complications |
| D005261 | Female Urogenital Diseases and Pregnancy Complications |
| D000091642 | Urogenital Diseases |