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To see if using ipod games can improve mental functioning
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| ipod games | Experimental | Administered ipod games with cognitive testing before and after |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| ipod games | Behavioral | Patients will be given ipod games for 4 weeks and tested in related and unrelated cognitive measures |
|
| Measure | Description | Time Frame |
|---|---|---|
| Improvement in cognitive test performance with iPod games | improvement in cognitive performance on a battery of cognitive tests (Psychometric Hepatic Encephalopathy Score, Inhibitory Control test and Verbal Learning) after iPod tests | 8 weeks |
| Measure | Description | Time Frame |
|---|---|---|
| Improvement in health-related quality of life | Sickness Impact Profile will be used before and after the treatment | 8 weeks |
| Improvement in brain MRI parameters | change in detailed imaging parameters related to diffusion tensor imaging, resting state and voxel-based morphometry |
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Inclusion Criteria:
Exclusion Criteria:
For MRI: inability to perform brain MRI is an exclusion
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Hunter Holmes McGuire VA Medical Center | Richmond | Virginia | 23249 | United States |
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| ID | Term |
|---|---|
| D006501 | Hepatic Encephalopathy |
| D005355 | Fibrosis |
| ID | Term |
|---|---|
| D017093 | Liver Failure |
| D048550 | Hepatic Insufficiency |
| D008107 | Liver Diseases |
| D004066 | Digestive System Diseases |
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| 4 weeks |
| D001928 |
| Brain Diseases, Metabolic |
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
| D009422 | Nervous System Diseases |
| D008659 | Metabolic Diseases |
| D009750 | Nutritional and Metabolic Diseases |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |