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Background: The main goal when diagnosing thyroid nodules, is to differentiate the few malignant from the overwhelming background of benign nodules. Currently available pre-operative tests are unable to rule out malignancy in a subset of patients and diagnostic thyroid surgery is necessary. Therefore, there is a need to develope the diagnostic tools for pre-operative diagnostic work-up of thyroid nodules.
The study will investigate a novel ultrasonographic technique called Shear Wave Elastography (SWE) in the pre-operative evaluation of thyroid nodules.
Aim:
To evaluate the diagnostic value of SWE in the pre-operative diagnosis of thyroid nodules in a tertiary surgical center.
Perspectives:
An optimization of the pre-operative risk-stratification and diagnosis of thyroid nodules can reduce unnecessary thyroid surgery, with a reduction in morbidity and better use of the economic and surgical resources.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Shear Wave Elastography | Other | All included patients have SWE performed |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Shear Wave Elastography (SWE) | Procedure |
|
| Measure | Description | Time Frame |
|---|---|---|
| Elasticity Index | Elasticity Index is obtained by SWE. | same day |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Kristine Z Rubeck, MD | Dep. of otorhinolaryngology, Aarhus University Hoapital | Principal Investigator |
| Viveque E Nielsen, MD PhD | Dep. of oto-rhinolarymgology and Head and Neck surgery, Aarhus Universtity Hospital | Study Director |
| Steen J Bonnema, PhD, DMSc | Dep. of Endocrinology, Odense University Hospital | Study Chair |
| Marie Louise Jespersen, MD | Dep. of Pathology, Aarhus University Hospital | Study Chair |
| Peer Christiansen, DMSc | Dep. og General Surgery, Aarhus University Hospital | Study Chair |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Øre-Næse-Halsafdeling H, Aarhus University Hospital | Aarhus C | 8000 | Denmark |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 33713190 | Derived | Bakkegaard P, Londero SC, Bonnema SJ, Nielsen VE, Jespersen ML, Swan KZ. Risk-stratification of thyroid nodules examined by 18FDG-PET/CT while ensuring congruity between imaging and histopathological localization. Eur Arch Otorhinolaryngol. 2021 Dec;278(12):4979-4985. doi: 10.1007/s00405-021-06733-5. Epub 2021 Mar 13. |
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| ID | Term |
|---|---|
| D016606 | Thyroid Nodule |
| ID | Term |
|---|---|
| D013964 | Thyroid Neoplasms |
| D004701 | Endocrine Gland Neoplasms |
| D009371 | Neoplasms by Site |
| D009369 | Neoplasms |
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| D006258 |
| Head and Neck Neoplasms |
| D004700 | Endocrine System Diseases |
| D013959 | Thyroid Diseases |